Rate dependence and adrenergic dependence of arrhythmias.

The American Journal of Cardiology
P Coumel

Abstract

The presence or absence of ventricular premature beats is often closely dependent on the heart rate, and the analysis of Holter recordings permits definition of the thresholds of frequency that are compatible with the extrasystolic phenomenon. The upper threshold above which the extrasystoles disappear, and the lower threshold below which they are not observed can be defined for longer or shorter periods of recording, and they can vary according to changes in the autonomic nervous system balance. The coupling interval of extrasystoles tends to shorten when the adrenergic drive increases, but is also strongly dependent on the duration of the immediately preceding RR/cycle lengths: the rate dependence and the adrenergic dependence explain why the coupling interval is often slightly variable rather than classically fixed. The complex interactions of these phenomena are more compatible with an underlying mechanism of parasystole, and determine the existence and the importance of repetitive activity following the initial premature beat in many forms of ventricular arrhythmias.

Citations

Oct 30, 1998·Pacing and Clinical Electrophysiology : PACE·J S GillA J Camm
Jun 1, 1993·Journal of Cardiovascular Electrophysiology·P Coumel
Mar 11, 2003·Journal of Cardiovascular Electrophysiology·Patrick AttuelSao Seing
Mar 8, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Martin J Schalij, Lieselot van Erven
Feb 11, 1998·Computers and Biomedical Research, an International Journal·D SapoznikovM S Gotsman
May 1, 1994·British Heart Journal·D C LefroyD W Davies
Oct 19, 2019·Journal of Cardiovascular Electrophysiology·Behzad PavriMarc Tecce

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.