PMID: 603639Dec 1, 1977Paper

Rate-limiting steps in the cytidine pathway for the synthesis of phosphatidylcholine and phosphatidylethanolamine

The Biochemical Journal
J P Infante

Abstract

An analysis of the available data on the cytidine pathway for the synthesis of phosphatidylcholine and phosphatidylethanolamine, by the logic derived from the theoretical principles of metabolic regulation, shows that the first two reactions catalysed by choline (ethanolamine) kinase and phosphocholine (phosphoethanolamine) cytidylyltransferase are rate-limiting, whereas the phosphocholine (phosphoethanolamine) transferase step is near equilibrium in rat liver.

Citations

Apr 1, 1984·Environmental Health Perspectives·S A Rooney
Oct 25, 2000·The Journal of Biological Chemistry·A LykidisS Jackowski
Aug 1, 1989·American Journal of Respiratory Cell and Molecular Biology·B E Miller, G E HooK
Jan 1, 1984·Critical Reviews in Microbiology·A Chopra, G K Khuller
Oct 26, 2011·Journal of Lipid Research·Aditya BansalTimothy R DeGrado
Jun 8, 2010·The Journal of Biological Chemistry·Hebe MarcucciClaudia Banchio
Aug 1, 1984·Veterinary Research Communications·H P Haagsman, L M van Golde
Oct 29, 1998·General Pharmacology·D Berkovic

Related Concepts

Choline Kinase
Cytidine
Liver
Nucleotidyltransferase
Phosphatidylcholines
Phosphatidylethanolamines
Polyribonucleotide Nucleotidyltransferase

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