Rate of adjacent segment disease in cervical disc arthroplasty versus single-level fusion: meta-analysis of prospective studies

Spine
Kushagra VermaKristin E Radcliff

Abstract

Meta-analysis of randomized controlled trials. To compare the reported incidence of adjacent segment disease (ASD) requiring surgical intervention between anterior cervical decompression and fusion (ACDF) and total disc arthroplasty (TDA). The concern for ASD has led to the development of motion-preserving technologies such as TDA. To date, however, no known study has sought to compare the incidence of ASD between ACDF and TDA in major prospective studies. A systematic review of IDE and non-IDE trials was performed using PubMed and Cochrane libraries. These databases were thoroughly searched for prospective randomized studies comparing ACDF and TDR. Six studies met the inclusion criteria for a meta-analysis and were used to report an overall rate of ASD for both ACDF and TDA. Pooling data from 6 prospective studies, the overall sample size at baseline was 1586 (ACDF = 777, TDA = 809) and at the final follow-up was 1110 giving an overall follow-up of 70%. Patients after an ACDF had a lower rate of follow-up overall than those after TDR (ACDF: 67.3% vs. TDR: 72.6%, P= 0.01). Thirty-six patients required adjacent-level surgery after an ACDF at 2 to 5 years of follow-up (6.9%) compared with 30 patients after a TDA (5.1%). The corre...Continue Reading

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Citations

Jun 9, 2014·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Zhiwei JiaDike Ruan
Feb 3, 2016·Clinical Orthopaedics and Related Research·Zhao-Ming ZhongJian-Ting Chen
Jun 30, 2015·Neurologia Medico-chirurgica·Taku Sugawara
Jan 19, 2016·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·S M KriegB Meyer
Apr 9, 2016·International Orthopaedics·Aaron J BucklandJeffrey M Spivak
May 24, 2015·The Spine Journal : Official Journal of the North American Spine Society·Nathan EvaniewGordon Guyatt
Aug 2, 2015·Physical Medicine and Rehabilitation Clinics of North America·Jean-Christophe A LevequeChris R Howe
Mar 4, 2015·The Spine Journal : Official Journal of the North American Spine Society·Martin SkeppholmClaes Olerud
Jun 18, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Shihua ZouHui Meng
Feb 2, 2017·Neurosurgical Focus·Timothy C Chin-See-ChongBiswadjiet S Harhangi
Dec 1, 2017·Clinical Spine Surgery : a Spine Publication·Justin MillerThomas Gianaris
Jan 10, 2018·Clinical Spine Surgery : a Spine Publication·Timothy T RobertsEdward C Benzel
Jun 13, 2017·Clinical Spine Surgery : a Spine Publication·Roland D DonkRonald H M A Bartels
Dec 30, 2016·Journal of Orthopaedic Surgery·Shan-Jin WangDe-Sheng Wu
May 11, 2019·Journal of Neurosurgery. Spine·Matthew F GornetAnne G Copay
Jul 19, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Martin SkeppholmTycho Tullberg
Jun 22, 2019·Journal of Neurosurgery. Spine·Ryan SnowdenRick Sasso
Oct 5, 2018·The Journal of the American Academy of Orthopaedic Surgeons·Theodore D KoreckijDaniel K Park
Oct 16, 2015·Journal of Spinal Disorders & Techniques·Iain S ElliottBruce V Darden
Mar 25, 2017·Current Reviews in Musculoskeletal Medicine·Kristen RadcliffSheeraz Qureshi
Mar 25, 2017·Current Reviews in Musculoskeletal Medicine·I David Kaye, Alan S Hilibrand
Aug 11, 2018·Journal of Orthopaedic Surgery and Research·Stavros OikonomidisRolf Sobottke
May 12, 2017·Current Reviews in Musculoskeletal Medicine·Dante LevenSheeraz Qureshi
Apr 2, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Michael P KellyNelson F SooHoo
Dec 15, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Chaojie YuBin Liang
Feb 27, 2018·Journal of Neurosurgical Sciences·Ammar H HawasliNeill M Wright

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