Abstract
A number of patients with persistent atrial fibrillation (AF) will not have sinus rhythm (SR) restored by direct current (DC) cardioversion. In patients with DC-refractory AF, oral pretreatment with sotalol increases the success rate at DC cardioversion. Consecutive patients with persistent AF, refractory at a first DC cardioversion, were prospectively included. A comparative group of patients with AF not refractory at DC cardioversion was studied. Oral sotalol treatment was started after unsuccessful DC cardioversion and given at least 7 days before renewed cardioversion. Four weeks after cardioversion, an electrocardiogram was performed. In all, 53 patients were enrolled in the study. Forty-three (81%) in the sotalol group regained sinus rhythm (SR): 10 (19%) of these converted pharmacologically and 33 (62%) after a second DC cardioversion; SR was never restored in 10 patients (19%). After 4 weeks, SR was maintained in 29 patients (67%). The comparative group included 132 patients and differed significantly from the DC-refractory patients only with regard to weight. After 4 weeks, SR was maintained by 50 patients (37%) in this group. In patients with persistent AF refractory to DC cardioversion, oral pretreatment with sotalol...Continue Reading
References
Feb 1, 1976·Circulation·W L HenryS E Epstein
Jul 1, 1991·The American Journal of Cardiology·I C Van GelderK I Lie
Dec 1, 1990·Circulation·S Juul-MöllerN Rehnqvist-Ahlberg
Sep 1, 1989·Pacing and Clinical Electrophysiology : PACE·M Wang, P Dorian
Jan 1, 1989·The American Journal of Cardiology·I C Van GelderK I Lie
Jan 15, 1989·The American Journal of Cardiology·H C DittrichP H Nicod
Apr 29, 1982·The New England Journal of Medicine·W B KannelP M McNamara
Mar 1, 1981·Circulation·R E KerberJ Kennedy
Oct 1, 1995·Journal of the American College of Cardiology·S H HohnloserF Baedeker
Aug 12, 1993·The American Journal of Cardiology·P Dorian, D Newman
Jun 1, 1996·Heart·S M SopherA J Camm
Sep 1, 1996·Journal of the American College of Cardiology·L BianconiM Santini
Dec 15, 1996·The American Journal of Cardiology·J CarlssonS Miketić
Feb 11, 1999·Journal of the American College of Cardiology·G BorianiB Magnani
Nov 24, 1999·The American Journal of Cardiology·H LiJ Windle
May 12, 2000·Journal of the American College of Cardiology·L P LaiS K Huang
Aug 5, 2000·European Heart Journal·M FrickM Rosenqvist
Dec 13, 2000·The American Journal of Cardiology·T Van NoordH J Crijns
Feb 28, 2001·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·V TaramascoS Lévy
Apr 6, 2001·Clinical Cardiology·M FrickM Rosenqvist
Jun 27, 2002·Journal of the American College of Cardiology·Richard L PageUNKNOWN BiCard Investigators