Rate of decline in serum PFOA concentrations after granular activated carbon filtration at two public water systems in Ohio and West Virginia.

Environmental Health Perspectives
Scott M BartellKyle Steenland

Abstract

Drinking water in multiple water districts in the Mid-Ohio Valley has been contaminated with perfluorooctanoic acid (PFOA), which was released by a nearby DuPont chemical plant. Two highly contaminated water districts began granular activated carbon filtration in 2007. To determine the rate of decline in serum PFOA, and its corresponding half-life, during the first year after filtration. Up to six blood samples were collected from each of 200 participants from May 2007 until August 2008. The primary source of drinking water varied over time for some participants; our analyses were grouped according to water source at baseline in May-June 2007. For Lubeck Public Service District customers, the average decrease in serum PFOA concentrations between May-June 2007 and May-August 2008 was 32 ng/mL (26%) for those primarily consuming public water at home (n = 130), and 16 ng/mL (28%) for those primarily consuming bottled water at home (n = 17). For Little Hocking Water Association customers, the average decrease in serum PFOA concentrations between November-December 2007 and May-June 2008 was 39 ng/mL (11%) for consumers of public water (n = 39) and 28 ng/mL (20%) for consumers of bottled water (n = 11). The covariate-adjusted average...Continue Reading

References

Jan 1, 1991·Journal of Biochemical Toxicology·J P Vanden HeuvelR E Peterson
Aug 12, 2006·Journal of Occupational and Environmental Medicine·Edward Anthony EmmettLeslie Michael Shaw
May 24, 2007·Toxicological Sciences : an Official Journal of the Society of Toxicology·Christopher LauJennifer Seed
Mar 18, 2008·Statistics in Medicine·Samuel P CaudillJames L Pirkle
Nov 14, 2008·Toxicological Sciences : an Official Journal of the Society of Toxicology·Inchio LouHugh A Barton
Feb 20, 2009·Journal of Occupational and Environmental Medicine·Giovanni CostaDario Consonni
May 26, 2009·International Journal of Hygiene and Environmental Health·Jürgen HölzerMichael Wilhelm
Aug 6, 2009·Environmental Health Perspectives·Kyle SteenlandTony Fletcher
Jan 6, 2010·Environmental Health Perspectives·Stephanie J FrisbeeAlan M Ducatman

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Citations

Apr 22, 2010·Environmental Health : a Global Access Science Source·Verónica M VieiraTony Fletcher
Apr 29, 2010·Environmental Health Perspectives·Kyle SteenlandDavid A Savitz
Oct 27, 2010·The Annals of Occupational Hygiene·Mary A KaiserMiguel A Botelho
Mar 1, 2012·Epidemiology·David A SavitzGregory A Wellenius
Feb 16, 2013·Environmental Health Perspectives·Sarah A UhlMichelle L Bell
Mar 14, 2013·Environmental Health Perspectives·Deborah J WatkinsGregory A Wellenius
Nov 28, 2013·Environmental Health Perspectives·Debapriya MondalTony Fletcher
Nov 28, 2013·Environmental Health Perspectives·Kyla W TaylorJulie L Daniels
Apr 21, 2012·American Journal of Epidemiology·Kristina W WhitworthMatthew P Longnecker
Feb 16, 2012·Journal of Exposure Science & Environmental Epidemiology·Scott M Bartell
May 21, 2013·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Kelly K FergusonJohn D Meeker
Dec 23, 2015·Environmental Science & Technology·Marc-André VernerMatthew Longnecker
Aug 21, 2015·Environmental Science & Technology·Ulla B MogensenEsben Budtz-Jørgensen
Aug 2, 2011·The Journal of Toxicological Sciences·Sarah S KnoxAlan M Ducatman
Jun 5, 2015·Environmental Health : a Global Access Science Source·Ulla B MogensenEsben Budtz-Jørgensen
Mar 8, 2012·Environmental Health : a Global Access Science Source·Jessica W NelsonThomas F Webster
Mar 10, 2015·Fertility and Sterility·Emily S BarrettInger Thune
Nov 20, 2016·Nature Reviews. Endocrinology·Joseph M Braun
Sep 21, 2013·Toxicological Sciences : an Official Journal of the Society of Toxicology·John F WambaughChristopher Lau
Dec 26, 2016·Toxicological Sciences : an Official Journal of the Society of Toxicology·Wen ZhaoBruno Hagenbuch
Sep 27, 2014·Environmental Health Perspectives·Andrea Winquist, Kyle Steenland
Jan 21, 2015·Occupational and Environmental Medicine·Kyle SteenlandAndrea Winquist
Jun 7, 2014·Environmental Health Perspectives·Olivier HumbletRobert A Hiatt
Jun 19, 2015·New Solutions : a Journal of Environmental and Occupational Health Policy : NS·Philippe Grandjean, Richard Clapp
Jun 24, 2017·Environment International·Rachel Rogers WorleyJeffrey Fisher
Jul 15, 2017·The Science of the Total Environment·Mei-Huei ChenPau-Chung Chen

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Methods Mentioned

BETA
activated carbon filtration
blood draw
blood draws

Software Mentioned

lme
R Development Core Team
R

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