Rate of three-dimensional neuroretinal rim thinning in glaucomatous eyes with optic disc haemorrhage

The British Journal of Ophthalmology
Yong Woo KimKi Ho Park

Abstract

To investigate the thinning rate of three-dimensional neuroretinal rim thickness (3D-NRT) in glaucoma eyes with optic disc haemorrhage (DH) and its relationship to retinal nerve fibre layer thickness (RNFLT) progression. Ninety-five (95) eyes of 95 glaucoma patients with initial DH in the inferotemporal (n=69) and superotemporal (n=26) regions and 48 eyes of 48 glaucoma patients without DH were retrospectively reviewed. The rates of change for 3D-NRT and RNFLT were compared by linear mixed-effect model. For the direct comparison between 3D-NRT and RNFLT, dynamic-range-based normalised coefficient was used. The effect of DH frequency on the rates of thinning of 3D-NRT and RNFLT was evaluated. During a mean 7-year follow-up, the rates of thinning of 3D-NRT (-5.69±4.88 µm/year) and RNFLT (-2.03±2.03 µm/year) at 7 o'clock were faster than those at other locations (all p<0.05) in DH eyes. The dynamic-range-based normalised rate of thinning was significantly faster for RNFLT (-2.06%±1.62%/year) than for 3D-NRT (-1.15%±1.10%/year, p<0.001) in DH eyes, but not in non-DH eyes (p=0.43). DH frequency in the inferotemporal region was associated with the thinning rate of 3D-NRT as well as RNFLT. DH eyes are associated with the progression o...Continue Reading

References

Aug 6, 2000·American Journal of Ophthalmology·K IshidaY Kitazawa
Jun 1, 2001·American Journal of Ophthalmology·S DranceUNKNOWN Collaborative Normal-Tension Glaucoma Study Group
Sep 1, 2001·American Journal of Ophthalmology·S K LawJ Caprioli
Dec 10, 2002·American Journal of Ophthalmology·Jae Kyoun Ahn, Ki Ho Park
Mar 26, 2003·American Journal of Ophthalmology·Yoshiki KonoYoshiaki Kitazawa
Jun 21, 2003·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·József BallaGyörgy Balla
Feb 21, 2006·Ophthalmology·Seok Hwan Kim, Ki Ho Park
May 22, 2009·Investigative Ophthalmology & Visual Science·Carlos Gustavo V De MoraesJeffrey M Liebmann
Mar 9, 2010·Investigative Ophthalmology & Visual Science·Luciana M AlencarFelipe A Medeiros
Oct 26, 2013·Survey of Ophthalmology·Min Hee Suh, Ki Ho Park
Feb 12, 2014·American Journal of Ophthalmology·Rafael L FurlanettoUNKNOWN Low-Pressure Glaucoma Treatment Study Group
Apr 3, 2014·Investigative Ophthalmology & Visual Science·Frédéric Pollet-VillardFlorent Aptel
Jul 31, 2014·The EPMA Journal·Katarzyna KonieczkaKe Yao
Dec 17, 2014·Investigative Ophthalmology & Visual Science·Vishva M DanthurebandaraBalwantray C Chauhan
Jan 23, 2016·Investigative Ophthalmology & Visual Science·Vishva M DanthurebandaraBalwantray C Chauhan
Mar 5, 2016·Investigative Ophthalmology & Visual Science·Young Kook KimKi Ho Park
Nov 8, 2016·Current Opinion in Ophthalmology·Ko Eun Kim, Ki Ho Park
Dec 21, 2017·Investigative Ophthalmology & Visual Science·Won June LeeJin Wook Jeoung
Jul 22, 2018·Investigative Ophthalmology & Visual Science·Yong Woo Kim, Ki Ho Park

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.