PMID: 3383469May 1, 1988Paper

Rate-responsive pacing with a pacemaker that detects respiratory rate (Biorate): clinical advantages and complications

Clinical Cardiology
C P LauA J Camm

Abstract

The respiratory-dependent pacemaker (RDP3 or MB-1, Biorate, Biotec International, S.p.A., Bologna, Italy) detects the respiratory rate by measuring thoracic impedance using a subcutaneous auxiliary lead. The sensed respiratory rate is used to determine the pacing rate response. This pacemaker had been implanted in 9 patients with a mean age of 58 (range 42-69) years. During symptom-limited treadmill exercise, rate-modulated pacing resulted in a significant increase in pacing rate (mean +/- SD, 124 +/- 10 vs. 71 +/- 3 beats/min p less than 0.001) and exercise capacity (343 +/- 147 vs. 463 +/- 120 s, p less than 0.05) compared to those achieved with constant rate ventricular pacing. Brief treadmill exercise tests showed appropriate rate response to increased walking speed and gradient. However, rate response was modified by arm swinging-induced motion artefact which affected the measured "impedance." Complications observed on follow-up included perforation of the auxiliary lead in 2 patients and symptomatic myopotential interference in 3 patients with the RDP3 pacemaker, all of whom required unit replacement. It is concluded that although the respiratory-dependent pacemaker can confer physiological benefit in patients with bradyc...Continue Reading

References

Jun 1, 1988·Pacing and Clinical Electrophysiology : PACE·C P LauA J Camm
May 1, 1986·Indian Heart Journal·M Khalilullah, V K Bahl
Jun 1, 1985·IEEE Transactions on Bio-medical Engineering·A V SahakianJ G Webster
Jul 1, 1982·Pacing and Clinical Electrophysiology : PACE·H Fischler
Sep 1, 1984·Pacing and Clinical Electrophysiology : PACE·J FetterF J Engman
Nov 1, 1961·Journal of Applied Physiology·P O ASTRAND, B SALTIN

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Citations

Mar 1, 1993·Clinical Cardiology·D KatritsisA J Camm
Dec 19, 1998·Journal of Cardiopulmonary Rehabilitation·C T SharpR G Haennel
Jan 1, 1992·Pacing and Clinical Electrophysiology : PACE·M SantomauroM Chiariello
Aug 1, 1992·Pacing and Clinical Electrophysiology : PACE·C P Lau
Feb 1, 1989·Pacing and Clinical Electrophysiology : PACE·C P LauA J Camm

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