Ratiometric fluorescent nanoprobes for visual detection: Design principles and recent advances - A review

Analytica Chimica Acta
Arafeh BigdeliM Reza Hormozi-Nezhad

Abstract

Signal generation techniques for visual detection of analytes have received a great deal of attention in various sensing fields. These approaches are considered to be advantageous when instrumentation cannot be employed, such as for on-site assays, point-of-care tests, and he althcare diagnostics in resource-constrained areas. Amongst various visual detection approaches explored for non-invasive quantitative measurements, ratiometric fluorescence sensing has received particular attention as a potential method to overcome the limitations of intensity-based probes. This technique relies on changes in the intensity of two or more emission bands (induced by an analyte), resulting in an effective internal referencing which improves the sensitivity of the detection. The self-calibration, together with the unique optophysical properties of nanoparticles (NPs) have made the ratiometric fluorescent nanoprobes more sensitive and reliable, which in turn, can result in more precise visual detection of the analytes. Over the past few years, a vast number of ratiometric sensing probes using nanostructured fluorophores have been designed and reported for a wide variety of sensing, imaging, and biomedical applications. In this work, a review o...Continue Reading

Citations

Sep 2, 2020·The Analyst·Arafeh BigdeliM Reza Hormozi-Nezhad
Sep 3, 2020·Critical Reviews in Food Science and Nutrition·Yong HanZhonghong Li
Oct 19, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yuanqiang HaoShu Chen
Mar 11, 2021·Advanced Materials·Jing WangBanglin Chen
May 4, 2021·Frontiers in Chemistry·Mindy Levine
May 15, 2021·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Teng ZhangNing Peng Wu
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Luigi Di Costanzo, Barbara Panunzi
May 28, 2021·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Linlin WangSeung Hyun Hur
Jun 17, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Xucan YuanZhili Xiong
Jul 16, 2021·Physical Chemistry Chemical Physics : PCCP·Zoraida FreixaFernando P Cossío
Aug 3, 2021·Analytical Biochemistry·Mahsa ImaniNosratollah Zarghami
Aug 13, 2021·ACS Chemical Neuroscience·Faezeh Shahdost-FardMohammad Reza Hormozi-Nezhad
Jul 14, 2020·ACS Applied Materials & Interfaces·Xiang-Jing KongJian-Rong Li
Aug 17, 2020·Environmental Science & Technology·Jieying LiangKang Liang
Jan 18, 2020·Journal of the American Chemical Society·Yaning WangSanzhong Luo

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