Ratiometric nanothermometer in vivo based on triplet sensitized upconversion

Nature Communications
Ming XuFuyou Li

Abstract

Temperature is an essential factor that counts for living systems where complicated vital activities are usually temperature dependent. In vivo temperature mapping based on non-contact optical approach will be beneficial for revealing the physiological phenomena behind with minimized influence to the organism. Herein, a highly thermal-sensitive upconversion system based on triplet-triplet annihilation (TTA) mechanism is pioneered to indicate body temperature variation sensitively over the physiological temperature range. The temperature-insensitive NaYF4: Nd nanophosphors with NIR emission was incorporated into the temperature-responsive TTA-upconversion system to serve as an internal calibration unit. Consequently, a ratiometric thermometer capable of accurately monitoring the temperature changes in vivo was developed with high thermal sensitivity (~7.1% K-1) and resolution (~0.1 K).

References

Jan 1, 1995·Annual Review of Physiology·G N Somero
May 1, 1997·Journal of Clinical Periodontology·I L Chapple
Feb 4, 1998·Biophysical Journal·O ZoharT Yoshioka
Oct 6, 1998·Archives of Internal Medicine·P A Mackowiak
Jan 15, 2004·Chemical Reviews·François Auzel
Sep 10, 2005·Annals of the Rheumatic Diseases·M BrennerP S Gulko
Mar 11, 2006·Journal of Biomedical Optics·Alec M De GrandJohn V Frangioni
Mar 28, 2008·Journal of Pharmacological and Toxicological Methods·Brian M SanchezKenneth S Kilgore
Nov 13, 2008·Journal of the American Chemical Society·Tanya N Singh-RachfordFelix N Castellano
May 8, 2009·Chemical Society Reviews·Feng Wang, Xiaogang Liu
Aug 5, 2009·Journal of the American Chemical Society·Tanya N Singh-RachfordFelix N Castellano
Nov 10, 2009·Nature Nanotechnology·Andrew M SmithShuming Nie
Jul 4, 2012·Nanoscale·Daniel Jaque, Fiorenzo Vetrone
Jul 6, 2012·Nanoscale·Carlos D S BritesLuís D Carlos
Jan 15, 2013·ACS Nano·Uéslen RochaDaniel Jaque
Mar 2, 2013·Chemical Society Reviews·Jianzhang ZhaoSong Guo
Jun 25, 2013·Chemical Society Reviews·Xu-dong WangRobert J Meier
Jul 23, 2013·Nature Protocols·Christian WürthUte Resch-Genger
Jul 1, 2014·Nanomedicine·Daniel JaqueJosé García Solé
Aug 29, 2014·Nature Methods·Guillaume BaffouLudovic Jullien
Dec 11, 2014·Chemical Reviews·Jing ZhouFuyou Li
Jul 16, 2015·Advanced Materials·Elizabeth Navarro CerónEmma Martín Rodríguez
Nov 18, 2015·Journal of Biophotonics·Blanca Del RosalFrancisco Sanz-Rodríguez
Jan 30, 2016·Advanced Materials·Paloma Rodríguez-SevillaDaniel Jaque
Feb 5, 2016·Physical Chemistry Chemical Physics : PCCP·Changqing YeZuoqin Liang
Feb 5, 2016·Nano Letters·Erving Clayton XimendesCarlos Jacinto
Mar 8, 2016·Chemical Communications : Chem Comm·Nobuhiro Yanai, Nobuo Kimizuka
Jun 10, 2016·Chemical Society Reviews·Mikhail A FilatovKatharina Landfester
Dec 23, 2016·Advanced Healthcare Materials·Erving Clayton XimendesNuria Fernández
Jan 7, 2017·The Journal of Physical Chemistry. B·Sven H C AskesSylvestre Bonnet

❮ Previous
Next ❯

Citations

Apr 24, 2019·Nanoscale·Erving C XimendesCarlos Jacinto
Jul 10, 2019·Chemistry : a European Journal·Chaoqun WangYi Lv
Feb 25, 2020·Angewandte Chemie·Nobuhiro Yanai, Nobuo Kimizuka
Jul 8, 2020·Nanoscale·Artur BednarkiewiczDaniel Jaque
Jul 17, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Peng DuLaihui Luo
Jul 30, 2020·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Lina WuXilin Sun
Aug 14, 2020·Chemical Communications : Chem Comm·Xianlong SuFuyou Li
Apr 23, 2020·Methods and Applications in Fluorescence·Ioana PorosnicuCarmen Tiseanu
Sep 30, 2020·Nature Methods·Jiajia ZhouDayong Jin
Aug 15, 2020·Frontiers in Chemistry·Fangfang LiuJinliang Liu
Mar 6, 2021·Analytical Chemistry·Lei DingDayong Jin
Mar 24, 2021·The Journal of Physical Chemistry Letters·Jianlei HanPengfei Duan
Mar 30, 2021·Journal of the American Chemical Society·Indranil RoyJ Fraser Stoddart
Jul 22, 2021·ACS Applied Materials & Interfaces·Kedar Bahadur ThapaZhenlan Fang
Sep 10, 2020·ACS Applied Materials & Interfaces·Wojciech PiotrowskiLukasz Marciniak
Dec 23, 2020·ACS Applied Materials & Interfaces·Joanna Drabik, Lukasz Marciniak
May 21, 2020·Biomacromolecules·Banu IyisanKatharina Landfester
Jul 6, 2019·ACS Applied Materials & Interfaces·Hak-Lae LeeJae-Hyuk Kim
Oct 28, 2019·ACS Applied Materials & Interfaces·Yunfei ShangChunhui Yang
Aug 21, 2019·The Journal of Physical Chemistry. B·Meredith M OgleAngel A Martí
Sep 29, 2019·ACS Applied Materials & Interfaces·Michele BackSetsuhisa Tanabe
Jan 10, 2020·Inorganic Chemistry·Yibo ChenZhao-Qing Liu
Dec 9, 2021·ACS Sensors·Gungun Lin, Dayong Jin
Dec 9, 2021·Biomedical Materials·Haoying HuangChunyan Li
Jan 4, 2022·ACS Applied Materials & Interfaces·Ilya E KolesnikovErkki Lähderanta

❮ Previous
Next ❯

Methods Mentioned

BETA
column chromatography
enzyme-linked immunosorbent assay

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry
Andrey TurshatovStanislav Baluschev
Cardiologia : bollettino della Società italiana di cardiologia
M GaspariniM Albertinazzi
Medical & Biological Engineering & Computing
J W Moore, R S Newbower
© 2022 Meta ULC. All rights reserved