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Rational design and adaptive management of combination therapies for Hepatitis C virus infection

bioRxiv

Aug 27, 2014

Ruian KeJames O. Lloyd-Smith

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Abstract

Recent discoveries of direct acting antivirals against Hepatitis C virus (HCV) have raised hopes of effective treatment via combination therapies. Yet rapid evolution and high diversity of HCV populations, combined with the reality of suboptimal treatment adherence, make drug resistance...read more

Mentioned in this Paper

Disease Management
Direct acting antivirals
Treatment Protocols
Pharmacokinetic Aspects
Population Group
Resistance Process
Drug Kinetics
Pharmacodynamics
Public Health Domain
Adherence (Attribute)
2
1
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  • Rational design and adaptive management of combination therapies for Hepatitis C virus infection

    bioRxiv

    Aug 27, 2014

    Ruian KeJames O. Lloyd-Smith

    PMID: 990008466

    DOI: 10.1101/008466

    Abstract

    Recent discoveries of direct acting antivirals against Hepatitis C virus (HCV) have raised hopes of effective treatment via combination therapies. Yet rapid evolution and high diversity of HCV populations, combined with the reality of suboptimal treatment adherence, make drug resistance...read more

    Mentioned in this Paper

    Disease Management
    Direct acting antivirals
    Treatment Protocols
    Pharmacokinetic Aspects
    Population Group
    2
    1

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