PMID: 9189277Jun 1, 1997Paper

Rats with area postrema lesions have lengthy eating and drinking bouts when fed ad libitum: implications for feedback inhibition of ingestive behavior

Behavioral Neuroscience
E M StrickerJ C Smith

Abstract

Ad libitum ingestive behavior of rats with area postrema lesions (APX) was monitored electronically every 6 s for 23 hr. Whereas control rats ate on average 32.2 g of food each day in 16.3 distinct bouts, rats with APX ate comparable amounts of food (28.6 g) in much fewer daily bouts (5.8) that were very large. Controls drank 38.4 ml of water daily in 17.8 bouts, whereas rats with APX consumed more than twice as much water (101.5 ml) in a similar number of bouts (18.5). Controls drank 5.3 ml of 0.5 M NaCl daily in 7.0 bouts, whereas rats with APX consumed 9 times as much saline (45.5 ml) in more bouts (18.2) that were relatively large. These and other results suggest that the area postrema plays an important role in detecting inhibitory signals generated by food or fluid intake and that feeding and drinking bouts may increase in size after APX, because the feedback inhibition provided by those signals is diminished.

Citations

Oct 31, 2000·Nutrition·E M Stricker, A F Sved

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
E M StrickerJ C Smith
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Carrie A SmithE M Stricker
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Myriam L HoffmannE M Stricker
© 2021 Meta ULC. All rights reserved