RBM4: a multifunctional RNA-binding protein

The International Journal of Biochemistry & Cell Biology
M Andrea Markus, Brian J Morris

Abstract

RBM4, also known as Lark, was described initially as having a role in circadian rhythm control in Drosophila. In the last 5 years data have emerged from studies of mammalian cells. It is now clear that RBM4 is an RNA-binding protein involved in diverse cellular processes that include alternative splicing of pre-mRNA, translation, and RNA silencing. Its structure, similar to other RNA-binding proteins, contains two RNA recognition motifs and a CCHC-type zinc finger. Here we review current information about the function of RBM4 and its localization within the cell. We then speculate about its possible relationship to disease.

References

Mar 12, 2003·The EMBO Journal·Ming-Chih LaiWoan-Yuh Tarn
May 26, 2004·The Journal of Biological Chemistry·Sven DiederichsCarsten Müller-Tidow
Nov 2, 2005·Molecular and Cellular Biology·Jung-Chun Lin, Woan-Yuh Tarn
Jun 17, 2006·The Journal of Biological Chemistry·Amar KarJane Y Wu
Aug 16, 2006·DNA and Cell Biology·M Andrea Markus, Brian J Morris
Feb 1, 2007·Proceedings of the National Academy of Sciences of the United States of America·Shihoko KojimaHajime Tei
Feb 8, 2007·Proceedings of the National Academy of Sciences of the United States of America·Jung-Chun LinWoan-Yuh Tarn
Mar 16, 2007·Leukemia·L YangM D Minden
May 24, 2007·Nature Reviews. Molecular Cell Biology·François-Michel BoisvertAngus I Lamond
Jun 19, 2007·Nature Reviews. Genetics·Jack D Keene
Nov 6, 2007·Biochimica Et Biophysica Acta·Avril A MorrisonMichael R Ladomery
Dec 8, 2007·Acta Biochimica Et Biophysica Sinica·Wei JinZhimin Shao

❮ Previous
Next ❯

Citations

Jul 13, 2013·Nature·Debashish RayTimothy R Hughes
Oct 9, 2009·Molecular & Cellular Proteomics : MCP·Yun W LamDavid A Matthews
Mar 26, 2013·PloS One·Chia-Chen LuWoan-Yuh Tarn
Oct 27, 2015·Cellular and Molecular Life Sciences : CMLS·Sarah Lück, Pål O Westermark
Sep 17, 2013·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Rui GuanXiao-Yan Wen
Dec 17, 2014·Briefings in Functional Genomics·Kate B CookQuaid D Morris
Jun 22, 2016·Scientific Reports·Hongmei YongBaorui Liu
Aug 30, 2020·The Journal of Immunology : Official Journal of the American Association of Immunologists·Long-Feng LuShun Li
Apr 19, 2020·Cellular and Molecular Life Sciences : CMLS·Uri Aceituno-ValenzuelaMaría Rosa Ponce
Mar 3, 2018·Acta Crystallographica. Section F, Structural Biology Communications·Adarsh Kumar, Subramanian Karthikeyan
Dec 19, 2017·Chemical Reviews·Xavier RamboutLynne E Maquat

❮ Previous
Next ❯

Related Concepts

Related Feeds

Alternative splicing

Alternative splicing a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Here is that latest research.

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.