RDoC and Psychopathology among Youth: Misplaced Assumptions and an Agenda for Future Research.

Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
Theodore P Beauchaine, Stephen P Hinshaw

Abstract

Now over 10 years old, the Research Domain Criteria (RDoC) has gained impressive traction in the adult psychopathology literature, but enthusiasm among child and adolescent psychopathologists lags somewhat behind. We consider possible reasons why RDoC has not been embraced fully in the child and adolescent literatures. We emphasize common, interrelated, and sometimes outdated assumptions that impede scientific progress that RDoC could facilitate. Traditionally, child and adolescent psychopathologists have used behavioral syndromes as gold standards against which biological markers are validated, even though behavioral syndromes are often measured with less precision; sought to identify large main effects of single biological functions on single behavioral syndromes, thereby ignoring (even if implicitly) the overwhelming etiological complexity of psychopathology; expected 1:1 correspondencies between biological functions and behaviors, despite evidence that core biological systems subserving behavior are functionally interdependent (i.e., modulate one another); and failed to consider neurobiological mechanisms of homotypic and heterotypic comorbidity and continuity. Using examples from our work, we show how a developmental, RDoC...Continue Reading

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Citations

Jun 12, 2020·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Andres De Los ReyesRafaella J Jakubovic
Dec 29, 2020·Research on Child and Adolescent Psychopathology·Paul J Frick
Feb 17, 2021·Psychoneuroendocrinology·Ellen JoplingJoelle LeMoult
Mar 16, 2021·Development and Psychopathology·Tiffany M Shader, Theodore P Beauchaine
Jun 8, 2021·Journal of the American Academy of Child and Adolescent Psychiatry·Ziv E BellUNKNOWN LAMS Consortium
Aug 10, 2021·Development and Psychopathology·Brendan OstlundKoraly E Pérez-Edgar
Oct 12, 2021·Journal of Autism and Developmental Disorders·Dana KamaraTheodore P Beauchaine

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Methods Mentioned

BETA
imaging techniques

Software Mentioned

RDoC Matrix
RDoC

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