Re-accumulation of macular pigment after successful macular hole surgery

The British Journal of Ophthalmology
Ferdinando BottoniGiovanni Staurenghi

Abstract

To investigate macular pigment optical density (MPOD) during follow-up of sealed macular holes and to study correlations of MPOD with progressive changes in spectral-domain optical coherence tomography (SD-OCT) and functional results. Consecutive patients (n=18) who had undergone successful vitrectomies for idiopathic macular holes were evaluated postoperatively at 1, 3, 6 and 9 months. At each follow-up visit, MPOD was measured with a modified confocal scanning laser ophthalmoscope and the outer retina evaluated by SD-OCT. The changes of MPOD postoperatively and the relationship of MPOD and SD-OCT findings to best corrected visual acuity were examined. MPOD did not change significantly throughout follow-up, from 0.49±0.22 (mean±SD) at month 1 to 0.42±0.18 at month 9. There was a tendency towards a significant association between amount of MPOD and recovery of external limiting membrane during follow-up (p=0.068). Best corrected visual acuity increased significantly from 0.24±0.12 before surgery to 0.65±0.25 at month 9. Recovery of the ellipsoid zone determined most of visual acuity improvement (p=0.024). MPOD was not associated with visual acuity changes (p=0.394). Revisualisation of macular pigment after successful macular ho...Continue Reading

References

May 1, 1991·Archives of Ophthalmology·N E Kelly, R T Wendel
Feb 1, 1987·American Journal of Epidemiology·S D WalterC K Wells
Jun 26, 1998·The British Journal of Ophthalmology·A von RückmannZ J Gregor
Jun 8, 2001·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·F C DeloriS A Burns
Aug 23, 2005·The British Journal of Ophthalmology·K NeelamS Beatty
Apr 28, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M TrieschmannD Pauleikhoff
Feb 17, 2009·American Journal of Ophthalmology·Alain Gaudric
Feb 25, 2011·Investigative Ophthalmology & Visual Science·Ferdinando BottoniGiovanni Staurenghi
Apr 19, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Masataka ShimozonoYasuo Kurimoto
Apr 24, 2014·Ophthalmology·Giovanni StaurenghiUNKNOWN International Nomenclature for Optical Coherence Tomography (IN•OCT) Panel

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Citations

Jul 20, 2018·Investigative Ophthalmology & Visual Science·Roberto dell'OmoFerdinando Bottoni
May 15, 2018·PloS One·Mario R RomanoGiovanni Cennamo
Oct 23, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Xhevat LumiMarko Hawlina
Nov 12, 2020·Translational Vision Science & Technology·Akira ObanaYuko Gohto
Feb 20, 2021·Journal of Ophthalmology·Roberto dell'OmoCiro Costagliola

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