Re-evaluation of retested nucleic acid-positive cases in recovered COVID-19 patients: Report from a designated transfer hospital in Chongqing, China

Journal of Infection and Public Health
Yan ChenXiaoqiu Xiao

Abstract

Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, Hubei Province, China [1], a large number of confirmed cases met the discharge criteria (one of which is two consecutive negative nucleic acid tests with an interval of at least 24 h) [2]. Previous studies have paid more attention to the epidemic situation of COVID-19 and patient diagnosis and treatment. Close attention also should be paid to the discharged patients. Surprisingly, a previous follow-up reported that some patients' nucleic acid retest results were positive again after discharge [3]. Factors impacting these follow-up test results should be further investigated. Since the first confirmed case was diagnosed in our hospital (Chongqing Emergency Medical Center, the designated transfer hospital) on February 4th, we confirmed a total of 17 cases. All patients infected with the novel coronavirus were transferred to a designated hospital in Southwest China's Chongqing by ambulance with an inbuilt negative-pressure chamber [4]. In the follow-up examination of these patients, RT-PCR tests were conducted again 3 days after discharged from the designated hospital. Four patients showed recurrence of positive results after a few days of discharge. Thus, we exam...Continue Reading

Citations

Sep 24, 2020·Reviews in Medical Virology·Eamon O MurchuPatricia Harrington
Oct 11, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Anna GidariDaniela Francisci
Oct 29, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Thi Loi DaoPhilippe Gautret
Feb 17, 2021·The Journal of Infection·Letícia Adrielle Dos SantosRoque Pacheco de Almeida
Jul 24, 2021·Influenza and Other Respiratory Viruses·Sara SadrFereshteh Ghiasvand
Aug 16, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Lijun LiangJie Wu

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