Reaction time-related activity reflecting periodic, task-specific cognitive control

Behavioural Brain Research
Anita D BarberStewart H Mostofsky

Abstract

Reaction time (RT) is associated with increased amplitude of the Blood Oxygen-Level Dependent (BOLD) response in cognitive control regions. The current study examined whether the Primary Condition (PC) effect and RT-BOLD effect both reflect the same cognitive control processes. In addition, RT-BOLD effects were examined in two Go/No-go tasks with different demands to determine whether RT-related activity is task-dependent, reflecting the recruitment of task-specific cognitive processes. Data simulations showed that RT-related activity could be distinguished from that of the primary condition if it is mean-centered. In that case, RT-related activity reflects periodically-engaged processes rather than "time-on-task" (ToT). RT-related activity was mostly distinct from that of the primary Go contrast, particularly for the perceptual decision task. Therefore, RT effects can reflect additional cognitive processes that are not captured by the PC contrast consistent with a periodic-engagement account. RT-BOLD effects occurred in a separate set of regions for the two tasks. For the task requiring a perceptual decision, RT-related activity occurred within occipital and posterior parietal regions supporting visual attention. For the task ...Continue Reading

References

Apr 24, 2002·Journal of Cognitive Neuroscience·Maurizio CorbettaGordon L Shulman
May 10, 2008·Neuron·Maurizio CorbettaGordon L Shulman
Sep 9, 2008·NeuroImage·Jack GrinbandJoy Hirsch
Sep 19, 2008·Journal of Neurophysiology·Justin L VincentRandy L Buckner
Apr 25, 2009·Brain : a Journal of Neurology·Stewart H MostofskyJames J Pekar
May 11, 2011·NeuroImage·Jack GrinbandJoy Hirsch
Jan 26, 2013·Current Opinion in Neurobiology·Jonathan D Power, Steven E Petersen
Mar 28, 2013·Journal of Cognitive Neuroscience·Anita D BarberStewart H Mostofsky

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Citations

Mar 24, 2016·Brain Imaging and Behavior·Anita D BarberStewart H Mostofsky
Sep 22, 2018·Human Brain Mapping·Luyao ChenLiping Feng

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