PMID: 8291658Feb 1, 1994

Reactive eosinophilic pulmonary vascular infiltration in patients with spontaneous pneumothorax

The American Journal of Surgical Pathology
E LunaJ Kleinerman


Prominent nonnecrotizing eosinophilic inflammation of muscular pulmonary arteries was seen in resected lung tissue from two patients with spontaneous pneumothorax. Other histologic features included reactive eosinophilic pleuritis (REP) and fibrobullous disease. Eosinophilic vascular infiltration was not contiguous to REP. In neither patient was there a specific and recognized cause of eosinophilic vasculitis. Both patients are without pulmonary symptoms 1 and 4 years after pneumothorax. Eosinophilic vascular infiltration initially suggested the diagnosis of allergic angiitis or pulmonary eosinophilic granuloma. These diagnoses were excluded by clinical and morphologic data. We subsequently reviewed 30 cases of lung tissue resected from patients with pneumothorax and found REP in 18 patients (60%) and mild pulmonary vascular and perivascular eosinophilia in five patients (17%). REP was present in all cases with eosinophilic vascular infiltration. We conclude that this eosinophilic vascular lesion is an unusual reaction in patients with REP and pneumothorax. Occasionally this lesion mimics allergic angiitis or eosinophilic granuloma. The pathogenesis is probably related to vascular transport of eosinophils to the injured pleural...Continue Reading


Apr 7, 2009·Indian Journal of Pediatrics·Nishith Kumar JetleyAbdul Lateef Softha
Feb 6, 2007·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Konstantin ShiloTeri J Franks
Sep 27, 2007·The American Journal of Surgical Pathology·Aashiyana KoreishiJoseph Misdraji
Jan 31, 2014·Archives of Pathology & Laboratory Medicine·Frank SchneiderKevin O Leslie
May 10, 2002·Pediatric Pulmonology·Bernhard ReschWilhelm D Müller
Nov 9, 2000·American Journal of Clinical Pathology·A L Katzenstein
Jan 6, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·S A Yousem

Related Concepts

Pulmonary Alveolar Structure
Churg-Strauss Syndrome
Pulmonary Artery Structure
Vascular Diseases
Lobar Bronchus Structure

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

Super-resolution Microscopy

Super-resolution microscopy is the term commonly given to fluorescence microscopy techniques with resolutions that are not limited by the diffraction of light. Here are the latest discoveries pertaining to super-resolution microscopy.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Related Papers

Bratislavské lekárske listy
G KhanbabaeeN Rezaei
The Thoracic and Cardiovascular Surgeon
B CelikM Kaptanoglu
The American Journal of Surgical Pathology
R Menzies, R Fraser
© 2020 Meta ULC. All rights reserved