PMID: 7336368Dec 1, 1981Paper

Reactive mesothelial proliferation: a necropsy study

Thorax
C D SheldonP J Gallagher

Abstract

To establish a histological standard against which surgical biopsy material could be compared, the degree of mesothelial proliferation was studied in 100 unselected necropsies. A minor degree of mesothelial hyperplasia was identified in 10 cases, usually close to areas of fibrous adhesions. Pleural plaques were present in 33 patients but there was no evidence of associated mesothelial proliferation. No mesothelial changes were noted in patients with empyema or pleural metastases. These findings indicated that the degree of mesothelial hyperplasia in common disorders of the pleura is relatively slight. Significant mesothelial proliferation in needle biopsies should therefore be viewed with considerable suspicion and, where clinically appropriate, be followed by further investigation.

References

Nov 25, 1977·Virchows Archiv. A, Pathological Anatomy and Histology·M Klima, F Gyorkey
Aug 1, 1975·American Journal of Clinical Pathology·D D Von Hoff, V LiVolsi
Jul 1, 1972·Journal of Clinical Pathology·G H Roberts, G M Campbell
May 1, 1970·Thorax·V Rous, J Studený
Jan 1, 1966·Acta Pathologica Et Microbiologica Scandinavica·L Meurman
Oct 1, 1963·The Journal of Pathology and Bacteriology·B NAYLOR

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Citations

Nov 1, 1982·Thorax·A Herbert, P J Gallagher
Sep 7, 2006·Diagnostic Cytopathology·B AroraBharat Rekhi
Dec 1, 1989·Experimental and Molecular Pathology·C StrangeS A Sahn
Jul 1, 1984·The Journal of Pathology·D Whitaker, K B Shilkin
Jan 1, 1995·International Journal of Psychiatry in Medicine·L B Hocking, H G Koenig

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