Reactivity of phenolic compounds towards free radicals under in vitro conditions

Journal of Food Science and Technology
Sindhu MathewZainul Akmar Zakaria

Abstract

The free radical scavenging activity and reducing power of 16 phenolic compounds including four hydroxycinnamic acid derivatives namely ferulic acid, caffeic acid, sinapic acid and p-coumaric acid, benzoic acid and its derivatives namely protocatechuic acid, gallic acid and vanillic acid, benzene derivatives namely vanillin, vanillyl alcohol, veratryl alcohol, veratraldehyde, pyrogallol, guaiacol and two synthetic antioxidants, butylated hydroxy anisole (BHA) and propyl gallate were evaluated using 1,1-Diphenyl-2-picrylhydrazyl radical (DPPH(•)), 2,2'-Azinobis-3- ethylbenzothiazoline-6-sulfonic acid radical (ABTS(+•)), Hydroxyl radical ((•)OH) and Superoxide radical (O2 (•-)) scavenging assays and reduction potential assay. By virtue of their hydrogen donating ability, phenolic compounds with multiple hydroxyl groups such as protocatechuic acid, pyrogallol, caffeic acid, gallic acid and propyl gallate exhibited higher free radical scavenging activity especially against DPPH(•) and O2 (•-). The hydroxylated cinnamates such as ferulic acid and caffeic acid were in general better scavengers than their benzoic acid counter parts such as vanillic acid and protocatechuic acid. All the phenolic compounds tested exhibited more than 85 ...Continue Reading

References

Jan 1, 1992·Critical Reviews in Food Science and Nutrition·F Shahidi, P K Wanasundara
Jan 1, 1990·Free Radical Biology & Medicine·R F HaseloffB Ebert
Jan 1, 1989·Critical Reviews in Food Science and Nutrition·K Herrmann
Jan 1, 1996·Free Radical Biology & Medicine·C A Rice-EvansG Paganga
Jun 25, 1999·Free Radical Biology & Medicine·R ReC Rice-Evans
Nov 24, 1999·Journal of Agricultural and Food Chemistry·F NatellaC Scaccini
Jan 26, 2002·Cancer Causes & Control : CCC·K K NicodemusA R Folsom
Mar 21, 2002·Journal of Agricultural and Food Chemistry·Hiroe KikuzakiHisaji Taniguchi
May 1, 2002·Redox Report : Communications in Free Radical Research·S Santosh KumarK B Sainis
May 30, 2002·Journal of Agricultural and Food Chemistry·B Matthäus
May 2, 2003·Journal of Agricultural and Food Chemistry·Rebecca J Robbins
Jul 22, 2004·Journal of Agricultural and Food Chemistry·Nikolaos NenadisHong-Yu Zhang
Aug 10, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Sindhu Mathew, T Emilia Abraham
Oct 14, 2006·Molecular Nutrition & Food Research·Jingli ZhangMargot A Skinner
Jul 29, 2009·Natural Product Reports·Alan CrozierMichael N Clifford
Sep 10, 2011·Oxidative Medicine and Cellular Longevity·Boguslaw Lipinski
Nov 3, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Pu JingJie Pang
Aug 21, 2013·BioMed Research International·José TeixeiraFernanda Borges
Feb 20, 2014·Chemical Research in Toxicology·Severina PacificoPietro Monaco
Sep 5, 2014·Journal of Agricultural and Food Chemistry·Shaoling LinPeter C K Cheung

❮ Previous
Next ❯

Citations

Jul 4, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jin-Seon YookYoun-Soo Cha
Mar 11, 2016·Archives of Pharmacal Research·Wael M Abdel-MageedAhmed A M Shoreit
Dec 23, 2015·Journal of the Science of Food and Agriculture·Kehan PeiShiyi Ou
Oct 27, 2016·Oxidative Medicine and Cellular Longevity·Alencar Kolinski MachadoIvana Beatrice Mânica da Cruz
Jan 18, 2017·Journal of Enzyme Inhibition and Medicinal Chemistry·Ljiljana JanjuševićBoris Pejin
Apr 19, 2018·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·Hengqiang ZhaoXiao Wang
Oct 31, 2018·Critical Reviews in Food Science and Nutrition·Sara SilvaManuela Pintado
Mar 4, 2020·Pharmacological Reports : PR·Neda AnastassovaMagdalena Kondeva-Burdina
Jul 22, 2020·Journal of Food Biochemistry·Alam Zeb
Sep 24, 2019·Journal of Biomolecular Structure & Dynamics·Tooba SiddiquiFahim Halim Khan
Aug 29, 2019·Critical Reviews in Food Science and Nutrition·Anurag Khatkar, Krishna Kant Sharma
May 7, 2019·Central Nervous System Agents in Medicinal Chemistry·Nayana Keyla Seabra de OliveiraLorane Izabel da Silva Hage-Melim
Aug 31, 2019·BioMed Research International·Thamizhiniyan VenkatesanYoung-Kyoon Kim
Jul 22, 2019·Journal of Fluorescence·Tooba SiddiquiFahim Halim Khan
Aug 22, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Antonella Di SottoLucia Nencioni
Oct 13, 2020·International Journal of Phytoremediation·Ritu ChaturvediManoj S Paul
Dec 9, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Veronika PetrulovaMiroslav Repcak
Nov 10, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Ali S AlqahtaniRiaz Ullah
Dec 22, 2020·Frontiers in Physiology·Henrique Silva, Nuno Miguel F Lopes
Jul 13, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Nguyen Hoai NguyenBich Hang Do
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Aleksandra PieczykolanRenata Nowak
Apr 8, 2017·Journal of Agricultural and Food Chemistry·Antonio Garcia-JimenezFrancisco García-Cánovas
Aug 11, 2021·Plants·Antonella FaisFrancesca Pintus
Jun 1, 2018·Journal of Agricultural and Food Chemistry·Nasreddine BenbettaiebFrédéric Debeaufort
Nov 7, 2021·Journal of the Science of Food and Agriculture·Yuqing SunJing Xie

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Medicinal Chemistry
Esra FındıkMahfuz Elmastaş
Journal of Agricultural and Food Chemistry
Hiroe KikuzakiHisaji Taniguchi
Journal of Acupuncture and Meridian Studies
Surendra Kumar Sharma, Ajay Pal Singh
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
Guang-Rong ZhaoLi-Bin Zhao
© 2021 Meta ULC. All rights reserved