Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging

Optics Express
Rick BezemerCan Ince

Abstract

Laser speckle imaging (LSI) is able to provide full-field perfusion maps of the renal cortex and allows quantification of the average LSI perfusion within an arbitrarily set region of interest and the recovery of LSI perfusion histograms within this region. The aim of the present study was to evaluate the use of LSI for mapping renal cortical microvascular perfusion and to demonstrate the capability of LSI to assess renal perfusion heterogeneities. The main findings were that: 1) full-field LSI measurements of renal microvascular perfusion were highly correlated to single-point LDV measurements; 2) LSI is able to detect differences in reperfusion dynamics following different durations of ischemia; and 3) renal microvascular perfusion heterogeneities can be quantitatively assessed by recovering LSI perfusion histograms.

References

Jan 29, 2000·Kidney International·J M CoremansG J Puppels
Apr 11, 2001·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A K DunnD A Boas
May 9, 2002·American Journal of Physiology. Renal Physiology·Tokunori YamamotoMichael S Goligorsky
Jan 1, 2003·Medical & Biological Engineering & Computing·K R ForresterR C Bray
Jul 16, 2003·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Alexander GorbachAllan D Kirk
Jul 23, 2003·Journal of the American Society of Nephrology : JASN·Joseph V Bonventre, Joel M Weinberg
Aug 18, 2004·Critical Care : the Official Journal of the Critical Care Forum·Rinaldo BellomoUNKNOWN Acute Dialysis Quality Initiative workgroup
Nov 4, 2004·The Journal of Surgical Research·Jason T FitzgeraldChristoph Troppmann
Feb 1, 2005·Lancet·Norbert LameireRaymond Vanholder
Sep 1, 2005·Burns : Journal of the International Society for Burn Injuries·C J StewartR C Bray
Jun 29, 2006·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Zheng WangRavi S Menon
Aug 24, 2006·American Journal of Physiology. Renal Physiology·Liping WuPhilip R Mayeux
Sep 28, 2006·Clinical and Experimental Pharmacology & Physiology·Paul M O'Connor
Sep 28, 2006·Clinical and Experimental Pharmacology & Physiology·Christian RosenbergerSamuel N Heyman
May 13, 2008·The Journal of Surgical Research·Alexander M GorbachEric A Elster
May 20, 2008·Molecular Medicine·Matthieu LegrandCan Ince
Feb 20, 2009·American Journal of Physiology. Renal Physiology·Matthieu LegrandCan Ince

❮ Previous
Next ❯

Citations

Oct 17, 2014·Current Opinion in Critical Care·Alexander ZarbockJohn A Kellum
Dec 7, 2014·Best Practice & Research. Clinical Anaesthesiology·Daniel De Backer, Arthur Durand
Dec 25, 2012·Critical Care Medicine·Daniel Stuart Martin, Michael Patrick William Grocott
Dec 15, 2015·Critical Care : the Official Journal of the Critical Care Forum·Chun-Yu WuUNKNOWN NTUH Center of Microcirculation Medical Research
Jun 24, 2014·IEEE Transactions on Bio-medical Engineering·Christopher G ScullyKi H Chon
Aug 2, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Lara Zafrani, Can Ince
Feb 14, 2013·Microvascular Research·Christian SturessonThomas M van Gulik
Jun 1, 2016·IEEE Transactions on Bio-medical Engineering·Christopher G ScullyKi H Chon
Sep 30, 2016·Scientific Reports·Hanne M van der KooijJoris Sprakel
Jan 23, 2018·Nature Reviews. Nephrology·John A Kellum, John R Prowle
Dec 6, 2018·Journal of Biophotonics·Zhendong GuoSung-Liang Chen
Oct 30, 2015·Journal of the American Society of Nephrology : JASN·Martin MatejovicUNKNOWN ADQI XIII Work Group
Jan 11, 2013·Biomedical Optics Express·Lipei Song, Daniel S Elson
Jun 10, 2014·Physiological Measurement·John Allen, Kevin Howell
Jan 15, 2015·American Journal of Physiology. Renal Physiology·Nicholas MitrouWilliam A Cupples
Apr 5, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Christopher G ScullyKi H Chon
Nov 3, 2016·Current Opinion in Critical Care·Hernando Gómez, John A Kellum
Mar 19, 2021·Frontiers in Immunology·Pierre-Olivier LudesAlexandre Mebazaa
May 24, 2021·Journal of Biomedical Optics·Wido HeemanE Christiaan Boerma

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Imaging in CNS

Here is the latest research on cell imaging and imaging modalities, including light-sheet microscopy, in the central nervous system.