Real-time continuous estimation of gas exchange by dual oximetry

Intensive Care Medicine
J RäsänenW L Garner


We designed a ventilation-perfusion index (VQI) to estimate venous admixture (Qsp/Qt) in a real-time fashion by simultaneous pulse and pulmonary artery oximetry in 17 patients with acute respiratory failure. Changes in Qsp/Qt were produced by altering the level of continuous positive airway pressure. VQI correlated well with Qsp/Qt (r = 0.78). This contrasts with the poor correlation found between Qsp/Qt and the commonly used oxygen tension based indices such as PaO2/FIO2 (r = -0.51), PaO2/PAO2 (r = 0.47), and PAO2-PaO2 (r = 0.23). The use of dual oximetry to derive a VQI appears to be a reliable and accurate method for real-time assessment of pulmonary gas exchange in patients with acute respiratory failure.


Oct 1, 1995·Journal of Cardiothoracic and Vascular Anesthesia·F SheikhA M O'Leary
Jan 1, 1988·Journal of Clinical Anesthesia·J RäsänenM R Hodges
Jan 1, 1988·Intensive Care Medicine·R J Fallat
Jan 1, 1993·Meditsinskaia tekhnika·I I ShitikovS B Arsen'ev
Jul 16, 2008·American Journal of Physiology. Lung Cellular and Molecular Physiology·Gustavo Matute-BelloThomas R Martin
Jan 1, 1989·Journal of Clinical Monitoring·J F Kelleher
Nov 16, 2013·Journal of Applied Physiology·J RäsänenNoam Gavriely

Related Concepts

Acute Disease
Monitoring, Physiologic
Oximetry, Pulse
Positive End-Expiratory Pressure
Pulmonary Artery Structure
Respiratory Failure
Ventilation-Perfusion Ratio

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