Real-Time Continuous Glucose Monitoring in Gestational Diabetes: A Randomized Controlled Trial

American Journal of Perinatology
Andrew S LaneAlfred Z Abuhamad

Abstract

To evaluate whether real-time continuous glucose monitoring improves glycemic control over intermittent self-monitoring of blood glucose in gestational diabetes. We performed a single-institution randomized controlled trial. Patients with gestational diabetes were randomized to use either real-time or blinded continuous glucose monitoring. The primary outcome was mean sensor glucose level during the fourth week of continuous glucose monitoring use. Secondary outcomes included glycemic control and a composite of obstetric and neonatal outcomes. Of the 40 enrolled patients, 12 (60%) patients in the blinded continuous glucose monitoring group and 11 (55%) in the real-time continuous glucose monitoring group completed 4 weeks of monitoring and were included in the final analysis. There was no significant difference in mean sensor glucose level between the blinded continuous glucose monitoring group (98.9 ± 8.9 mg/dL) and the real-time continuous glucose monitoring group (107.5 ± 11.4 mg/dL). There were also no significant differences in the time spent in glycemic target, maternal, or neonatal outcomes. Our study shows that the use of continuous glucose monitoring with real-time feedback did not significantly decrease mean glucose v...Continue Reading

Citations

Dec 15, 2019·Clinical and Experimental Pharmacology & Physiology·Lihong ZhaoBingjin Li
Apr 29, 2021·Journal of Medical Internet Research·Claudia EberleStefanie Stichling
Jun 13, 2021·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·George GrunbergerJeff Unger

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