Real-time continuous monitoring of cerebral blood flow autoregulation using near-infrared spectroscopy in patients undergoing cardiopulmonary bypass.

Stroke; a Journal of Cerebral Circulation
Kenneth BradyCharles W Hogue

Abstract

Individualizing mean arterial blood pressure targets to a patient's cerebral blood flow autoregulatory range might prevent brain ischemia for patients undergoing cardiopulmonary bypass (CPB). This study compares the accuracy of real-time cerebral blood flow autoregulation monitoring using near-infrared spectroscopy with that of transcranial Doppler. Sixty adult patients undergoing CPB had transcranial Doppler monitoring of middle cerebral artery blood flow velocity and near-infrared spectroscopy monitoring. The mean velocity index (Mx) was calculated as a moving, linear correlation coefficient between slow waves of middle cerebral artery blood flow velocity and mean arterial blood pressure. The cerebral oximetry index was calculated as a similar coefficient between slow waves of cerebral oximetry and mean arterial blood pressure. When cerebral blood flow is autoregulated, Mx and cerebral oximetry index vary around zero. Loss of autoregulation results in progressively more positive Mx and cerebral oximetry index. Mx and cerebral oximetry index showed significant correlation (r=0.55, P<0.0001) and good agreement (bias, 0.08+/-0.18, 95% limits of agreement: -0.27 to 0.43) during CPB. Autoregulation was disturbed in this cohort dur...Continue Reading

References

Apr 1, 1993·Anesthesia and Analgesia·R M SchellJ G Reves
May 30, 1998·The Journal of Thoracic and Cardiovascular Surgery·L C WagerleD A Davis
Aug 30, 2003·Stroke; a Journal of Cerebral Circulation·Luzius A SteinerMarek Czosnyka
Jul 16, 2005·Stroke; a Journal of Cerebral Circulation·M ReinhardA Hetzel
Mar 7, 2006·The Journal of Thoracic and Cardiovascular Surgery·Robert MoracaR Alan Hall
Jun 23, 2006·Anesthesia and Analgesia·Charles W HogueJoseph E Arrowsmith
Jul 22, 2006·Stroke; a Journal of Cerebral Circulation·Rebecca F GottesmanGuy M McKhann
May 22, 2007·Journal of Neurotrauma·Susan L BrattonDavid W Wright
Sep 1, 2007·Stroke; a Journal of Cerebral Circulation·Ken M BradyDonald H Shaffner
Sep 23, 2008·Neurocritical Care·Luzius A SteinerMarek Czosnyka
Jan 8, 2009·Neurocritical Care·Marek CzosnykaLuzius A Steiner

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Citations

Apr 3, 2012·Journal of Clinical Monitoring and Computing·T W L ScheerenL A Schwarte
Sep 1, 2012·Neurocritical Care·Robert D StevensWade S Smith
Aug 26, 2011·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Jacques T YadeauMichael Gordon
Aug 15, 2013·Pediatric Research·Jessica A HowlettJennifer K Lee
Jan 20, 2012·The New England Journal of Medicine·Ola A SelnesGuy M McKhann
Nov 23, 2011·Anesthesia and Analgesia·Brijen JoshiCharles W Hogue
Feb 9, 2012·Anesthesia and Analgesia·Jennifer K LeeDonald H Shaffner
Sep 1, 2013·Anesthesia, Essays and Researches·Charu MahajanParmod Kumar Bithal
Apr 8, 2014·Medical Engineering & Physics·Christian ZweifelMarek Czosnyka
Jul 22, 2014·Resuscitation·Jennifer K LeeDonald H Shaffner
May 27, 2014·The American Journal of Emergency Medicine·Thomas J AbramoGregory Albert
Dec 7, 2014·Best Practice & Research. Clinical Anaesthesiology·Jochen Steppan, Charles W Hogue
Sep 19, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Markus KredelRalf M Muellenbach
Jul 30, 2011·Current Opinion in Anaesthesiology·Ganne S Umamaheswara Rao, Padmaja Durga
Dec 14, 2012·Current Opinion in Anaesthesiology·Karsten BartelsJoseph P Mathew
Jan 24, 2015·Expert Review of Neurotherapeutics·Joseph DonnellyMarek Czosnyka
Oct 28, 2015·Scandinavian Journal of Clinical and Laboratory Investigation·Anton LundHenrik Sørensen
Mar 19, 2014·The Journal of Thoracic and Cardiovascular Surgery·Masahrio OnoCharles W Hogue
Jan 22, 2014·The Annals of Thoracic Surgery·Masahiro OnoCharles W Hogue
Nov 28, 2013·The American Journal of Emergency Medicine·Thomas AbramoMark Meredith
Dec 26, 2012·Revista española de anestesiología y reanimación·P Catalán EscuderoJ García Fernández
Jan 8, 2013·The American Journal of Cardiology·Cathy De DeyneJo Dens
Nov 6, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Masahiro OnoCharles W Hogue
Oct 5, 2014·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Andrew WeatherallJonathan Egan
Oct 7, 2015·Neurocritical Care·Robert D StevensRhonda Cadena
Mar 20, 2013·Paediatric Anaesthesia·Jennifer K LeeEdward S Ahn
Nov 13, 2014·The Laryngoscope·Joshua A HellerMenachem M Weiner

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