Real-time intra-fraction motion management in breast cancer radiotherapy: analysis of 2028 treatment sessions

Radiation Oncology
D ReitzS Corradini

Abstract

Intra-fraction motion represents a crucial issue in the era of precise radiotherapy in several settings, including breast irradiation. To date, only few data exist on real-time measured intra-fraction motion in breast cancer patients. Continuous surface imaging using visible light offers the capability to monitor patient movements in three-dimensional space without any additional radiation exposure. The aim of the present study was to quantify the uncertainties of possible intra-fractional motion during breast radiotherapy. One hundred and four consecutive patients that underwent postoperative radiotherapy following breast conserving surgery or mastectomy were prospectively evaluated during 2028 treatment sessions. During each treatment session the patients' motion was continuously measured using the Catalyst™ optical surface scanner (C-RAD AB, Sweden) and compared to a reference scan acquired at the beginning of each session. The Catalyst system works through an optical surface imaging with light emitting diode (LED) light and reprojection captured by a charge coupled device (CCD) camera, which provide target position control during treatment delivery with a motion detection accuracy of 0.5 mm. For 3D surface reconstruction, t...Continue Reading

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Citations

Jun 13, 2019·Journal of Applied Clinical Medical Physics·Sandra Helene HattelJakob Borup Thomsen
Aug 27, 2019·Tumori·Rosalinda RicottiBarbara Alicja Jereczek-Fossa
Mar 1, 2020·Radiation Oncology·Konstantin Christoph KobanStefanie Corradini
Sep 12, 2020·Radiation Oncology·Lukas NiererStefanie Corradini
Jul 25, 2019·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Montserrat PazosStefanie Corradini
Aug 2, 2020·Radiation Oncology·P FreisledererV Batista
Jan 14, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Jéssica Caroline LizarJuliana Fernandes Pavoni
Feb 27, 2021·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Matthew MouawadStewart Gaede
Apr 3, 2021·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Nienke HoekstraJean-Philippe Pignol
Aug 25, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Zhibin LiSen Bai
Oct 10, 2021·Radiology and Oncology·Elham PiruzanHojjat Mahani

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Methods Mentioned

BETA
X-ray

Software Mentioned

RAD Catalyst
plot3D
c4D
software
MATLAB
ggplot2
R
TOST
Oncentra
Catalyst

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