Real-time monitoring of lipid transfer between vesicles and hybrid bilayers on Au nanoshells using surface enhanced Raman scattering (SERS)

Nanoscale
Janardan KunduNaomi J Halas

Abstract

To investigate the dynamics of exchange/transfer of lipids between membranes, we have studied the interaction of donor-deuterated DMPC vesicles with DMPC hybrid bilayers on Au nanoshells using SERS. Experimental data confirm partial lipid exchange/transfer in the outer leaflet of the hybrid bilayer. The kinetics of the exchange/transfer process follows a first order process with a rate constant of 1.3 x 10(-4) s(-1). Changes in lipid phase behavior caused by the exchange/transfer process were characterized using generalized polarization measurements. In situ lipid transfer can potentially be utilized for preparation of asymmetric supported lipid bilayers and for incorporation of reporter lipids in biological membranes.

References

Sep 19, 1977·Biochimica Et Biophysica Acta·G Duckwitz-peterleinP Overath
Dec 11, 1992·Biochimica Et Biophysica Acta·R E Brown
Jul 14, 1987·Biochemistry·J R SilviusM Zuckermann
May 16, 2000·Chemistry and Physics of Lipids·M Langner, K Kubica
Feb 1, 2007·Journal of the American Chemical Society·Neil A AndersonKimberly A Briggman
Dec 22, 2007·Protein Science : a Publication of the Protein Society·Trevor H Yeats, Jocelyn K C Rose
Apr 30, 2008·Chemical Society Reviews·Surbhi LalNaomi J Halas
Oct 15, 2008·The Journal of Physical Chemistry. B·Angelica WikströmBengt Kasemo
Jan 31, 2009·Journal of the American Chemical Society·Angelika KunzeSofia Svedhem

❮ Previous
Next ❯

Citations

Mar 11, 2011·Biomacromolecules·S Van VlierbergheE Schacht
Feb 8, 2013·The Journal of Physical Chemistry. B·Aundrea R Piper-FeldkampScott M Reed
Apr 7, 2010·The Journal of Physical Chemistry. B·Marilyn R MackiewiczScott M Reed
Apr 22, 2011·Physical Chemistry Chemical Physics : PCCP·Kyle C BantzChristy L Haynes
Apr 5, 2011·Annual Review of Analytical Chemistry·Zachary D Schultz, Ira W Levin
Aug 25, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·James R MatthewsJason H Hafner
Jul 13, 2016·ACS Applied Materials & Interfaces·Kwanghyun KimJi-Hyun Jang
Aug 6, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Jay P Kitt, Joel M Harris
Jan 27, 2015·The Journal of Physical Chemistry. C, Nanomaterials and Interfaces·Reid E MessersmithScott M Reed
Dec 15, 2011·The Journal of Physical Chemistry Letters·Aoune Barhoumi, Naomi J Halas
Jul 7, 2017·Physical Chemistry Chemical Physics : PCCP·Poornima Budime SanthoshEthayaraja Mani
Apr 2, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Alaaldin M AlkilanyCatherine J Murphy
Jun 7, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Maryam ZareJoel M Harris
Nov 14, 2018·The Journal of Physical Chemistry Letters·Vesna ŽivanovićJanina Kneipp
Aug 15, 2019·ACS Applied Materials & Interfaces·Ian R BruzasLaura B Sagle

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved