Real time tracking in liver SBRT: comparison of CyberKnife and Vero by planning structure-based γ-evaluation and dose-area-histograms

Physics in Medicine and Biology
T SothmannT Gauer

Abstract

The purpose of this study was to evaluate and compare two clinical tracking systems for radiosurgery with regard to their dosimetric and geometrical accuracy in liver SBRT: the robot-based CyberKnife and the gimbal-based Vero. Both systems perform real-time tumour tracking by correlating internal tumour and external surrogate motion. CyberKnife treatment plans were delivered to a high resolution 2D detector array mounted on a 4D motion platform, with the platform simulating (a) tumour motion trajectories extracted from the corresponding CyberKnife predictor log files and (b) the tumour motion trajectories with superimposed baseline-drift. Static reference and tracked dose measurements were compared and dosimetric as well as geometrical uncertainties analyzed by a planning structure-based evaluation. For (a), γ-passing rates inside the CTV (γ-criteria of 1% / 1 mm) ranged from 95% to 100% (CyberKnife) and 98% to 100% (Vero). However, dosimetric accuracy decreases in the presence of the baseline-drift. γ-passing rates for (b) ranged from 26% to 92% and 94% to 99%, respectively; i.e. the effect was more pronounced for CyberKnife. In contrast, the Vero system led to maximum dose deviations in the OAR between  +1.5 Gy to +6.0 Gy (Cy...Continue Reading

References

Jan 31, 2004·Seminars in Radiation Oncology·Martin J Murphy
Nov 17, 2004·Medical Physics·Achim SchweikardJohn Adler
Apr 14, 2009·International Journal of Radiation Oncology, Biology, Physics·Mischa HoogemanBen Heijmen
Aug 19, 2009·Physics in Medicine and Biology·G G EchnerW Schlegel
Sep 8, 2010·Technology in Cancer Research & Treatment·W KilbyC R Maurer
Feb 15, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Tom DepuydtMark De Ridder
Apr 19, 2011·International Journal of Radiation Oncology, Biology, Physics·Kathleen MalinowskiWarren D D'Souza
Aug 6, 2011·Medical Physics·Sonja DieterichCheng Yu
Aug 20, 2011·International Journal of Computer Assisted Radiology and Surgery·Floris ErnstAchim Schweikard
Jul 17, 2012·Zeitschrift für medizinische Physik·Mihaela Rosu, Geoffrey D Hugo
Feb 13, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Tom DepuydtMark De Ridder
Aug 10, 2013·Medical Physics·B PoppeK Willborn
Nov 19, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Kenneth PoelsMark De Ridder
Oct 2, 2014·Zeitschrift für medizinische Physik·Carsten GrohmannFlorian Cremers
Dec 3, 2014·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Kenneth PoelsMark De Ridder
May 13, 2015·International Journal of Radiation Oncology, Biology, Physics·Manuela BurgheleaMark de Ridder
May 20, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Kenneth PoelsMark De Ridder

❮ Previous
Next ❯

Citations

Jun 2, 2016·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Oliver BlanckBjörn Poppe
Nov 4, 2016·Medical Physics·Cornelis Ph KamerlingUwe Oelfke
Mar 1, 2017·International Journal of Radiation Oncology, Biology, Physics·Mark ChanOliver Blanck
Feb 17, 2018·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Tobias GauerRené Werner
Jan 10, 2018·Physics in Medicine and Biology·H PrasetioC Bert
Oct 17, 2019·Physics in Medicine and Biology·Marc ZieglerChristoph Bert
May 31, 2019·Physics in Medicine and Biology·Monika TulikZbisław Tabor
Mar 27, 2020·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Daniela SchmittChristos Moustakis
Apr 23, 2021·Physics in Medicine and Biology·Tessa N van de LindtJan-Jakob Sonke
Oct 17, 2020·Medical Physics·Frederic MadestaRené Werner
May 22, 2021·Physical and Engineering Sciences in Medicine·Sankar ArumugamMark Lee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
Laure VieillevigneRegis Ferrand
© 2021 Meta ULC. All rights reserved