Real-World Integration of a Sepsis Deep Learning Technology Into Routine Clinical Care: Implementation Study

JMIR Medical Informatics
Mark P SendakCara O'Brien

Abstract

Successful integrations of machine learning into routine clinical care are exceedingly rare, and barriers to its adoption are poorly characterized in the literature. This study aims to report a quality improvement effort to integrate a deep learning sepsis detection and management platform, Sepsis Watch, into routine clinical care. In 2016, a multidisciplinary team consisting of statisticians, data scientists, data engineers, and clinicians was assembled by the leadership of an academic health system to radically improve the detection and treatment of sepsis. This report of the quality improvement effort follows the learning health system framework to describe the problem assessment, design, development, implementation, and evaluation plan of Sepsis Watch. Sepsis Watch was successfully integrated into routine clinical care and reshaped how local machine learning projects are executed. Frontline clinical staff were highly engaged in the design and development of the workflow, machine learning model, and application. Novel machine learning methods were developed to detect sepsis early, and implementation of the model required robust infrastructure. Significant investment was required to align stakeholders, develop trusting relati...Continue Reading

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Citations

Nov 20, 2020·Journal of Medical Internet Research·Sahil SandhuMark P Sendak
Feb 25, 2021·Journal of Gastroenterology and Hepatology·Dennis L Shung, Joseph J Y Sung
Feb 10, 2021·Journal of Medical Internet Research·Enrico SantusCharlotta Lindvall
Apr 3, 2021·Journal of Biomedical Informatics·Yan JiaIbrahim Habli
Jun 1, 2021·Frontiers in Medicine·Miao WuJie Wei
Aug 6, 2021·Journal of the American Medical Informatics Association : JAMIA·Birju S PatelNigam H Shah
Aug 24, 2021·Journal of the American Medical Informatics Association : JAMIA·Sehj KashyapNigam H Shah
Sep 11, 2021·NPJ Digital Medicine·Supreeth P ShashikumarShamim Nemati
Sep 10, 2021·Journal of the American Medical Informatics Association : JAMIA·Mark P SendakSuresh Balu
Sep 10, 2021·Journal of the American Medical Informatics Association : JAMIA·Jessica M SchwartzKenrick D Cato
Oct 28, 2021·Clinical and Translational Science·Elmer V BernstamMichael J Becich
Jan 23, 2020··Michael GaoMadeleine Clare Elish

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Clinical Trials Mentioned

NCT03655626

Software Mentioned

Epic Systems
Sepsis
Epic
Sepsis Watch
Commodity
Go
Live

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