Abstract
The production of vinyl chloride (VC) and polyvinyl chloride (PVC) involves the use of various chemicals, some known to be toxic and potentially or definitely carcinogenic. The related potential risk often has not been properly investigated. Updated cancer mortality among different subgroups of workers employed in a VC-PVC production plant located in Porto Marghera (Italy) was re-analyzed using an internal reference group of workers with low (or null) exposure to VC. Mortality of 1658 male workers was analyzed by Poisson regression. Relative risks (RRs) and 95% confidence intervals (CIs) for blue collar workers and their specific subgroups of PVC baggers, PVC compound, autoclave and other blue collar workers were calculated using technicians and clerks as an internal reference group. The follow-up covered the period 1972-1999. Significantly increased mortality rates were observed for all causes of death among the whole blue collar workforce (RR = 1.55; 95% CI = 1.03-2.35; 229 deaths), PVC baggers (1.72; 95% CI = 1.04-2.83; 49 deaths) and PVC compound workers (1.71; 95% CI = 1.09-2.67; 72 deaths). Liver cancer, including angiosarcoma, was increased among autoclave workers (9.57; 95% CI = 3.71-24.68; 7 deaths) and cardiovascular ...Continue Reading
References
Mar 1, 1978·Scandinavian Journal of Work, Environment & Health
Oct 1, 1992·American Journal of Epidemiology·K SteenlandS Adams
Jun 1, 1991·Scandinavian Journal of Work, Environment & Health·L SimonatoI Lundberg
Jan 1, 1990·American Journal of Industrial Medicine·R PirastuC Maltoni
Jan 1, 1988·American Journal of Industrial Medicine·J SiemiatyckiM Gérin
Dec 1, 1996·Statistical Methods in Medical Research·A Gelman, D B Rubin
Oct 27, 2001·Epidemiology·E WardL Simonato
Jun 1, 2002·Occupational and Environmental Medicine·R-H WongT-J Cheng
May 24, 2003·Journal of Occupational and Environmental Medicine·Richard LewisKenneth A Mundt
May 29, 2003·Occupational and Environmental Medicine·G MastrangeloS Pavanello
Jun 28, 2003·Scandinavian Journal of Work, Environment & Health·Paolo BoffettaLinda D Dell
Sep 27, 2003·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·C BosettiJ K McLaughlin
Jun 24, 2004·BMJ : British Medical Journal·Richard DollIsabelle Sutherland
Aug 4, 2004·Environmental Health Perspectives·Giuseppe MastrangeloDiego Martines
Jan 20, 2005·Journal of Clinical Nursing·Ken Proctor, Tim Welbourn
Aug 28, 2007·International Journal of Occupational and Environmental Health·Stefano ParodiPierluigi Cocco
Jan 24, 2008·BMC Public Health·Valerio GennaroFabio Montanaro
Sep 1, 1981·Scandinavian Journal of Work, Environment & Health·W F Diller
Sep 26, 2012·Annali Dell'Istituto Superiore Di Sanità·Lucia FazzoPietro Comba
Oct 1, 2005·Epidemiology and Infection·Emilia Vynnycky
Citations
Jun 12, 2010·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Paul G Shiels
Jun 17, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Richard C ThompsonShanna H Swan
Jan 25, 2012·Journal of Toxicologic Pathology·Toshinori YoshidaTakanori Harada
Nov 20, 2012·Hepatitis Monthly·Mario UccelloMariano Malaguarnera
Feb 24, 2016·Journal of Occupational Medicine and Toxicology·Roberto CappellettiValerio Gennaro
Jul 14, 2010·The Science of the Total Environment·Gösta AxelssonGerd Sallsten
May 23, 2009·Seminars in Oncology·Hatem SolimanDavid Thomas
Oct 23, 2014·Journal of Surgical Oncology·David M Thomas, Mandy L Ballinger
Feb 12, 2010·FEMS Microbiology Reviews·Timothy E MattesNicholas V Coleman
Jun 7, 2014·Environmental Research·Michael HendryxBo-Chiuan Chen
Apr 10, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Elisa FrullantiCarlo Zocchetti
Mar 19, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Giuseppe MastrangeloUgo Fedeli
Jan 24, 2008·BMC Public Health·Valerio GennaroFabio Montanaro
Mar 7, 2017·Disaster Medicine and Public Health Preparedness·Alice M ShumateMary Anne Duncan
Sep 1, 2015·Toxicology and Industrial Health·Mansour Rezazadeh AzariZahra Yazdanbakhsh
Dec 22, 2016·Molecular Medicine Reports·Caterina LeddaVenerando Rapisarda
May 12, 2016·World Journal of Hepatology·Venerando RapisardaGaetano Bertino
Oct 31, 2021·Environmental Toxicology·Igor N ZelkoSanjay Srivastava