PMID: 6986348Jan 1, 1980Paper

Reappraisal of extravascular lung thermal volume as a measure of pulmonary edema

Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
W H NobleG Caskanette

Abstract

Previous papers have evaluated extravascular thermal volume of the lung (ETVL) as a measure of lung water by using median transit time (tmed) rather than the correct mean transit time (tmean). Calculation of ETVL using tmean (ETVLmean) and tmed (ETVLmed) gave an excellent relationship, ETVLmean = 1.48 ETVLmed - 0.74 (r = 0.99). This allowed us to calculate a new ratio of ETVLmean to PETW = 1.55 +/- 0.17, WHERE PETW is the postmortem value of pulmonary extravascular tissue weight. Thermistors were placed in dogs to determine the contribution of chest wall, pleural and pericardial fluid, left heart, bronchi, and lung gas to the ETVL measurement. We found ETVLmean greater than PETW because of thermal distributioninto left heart (18 +/- 2% of ETVL), bronchi (estimate 7% of ETVL), pulmonary arteries and veins (estimate 7% of ETVL), and perhaps a small portion of chest wall. We could not detect any portion of lung gas or pleural or pericardial effusions as a part of the ETVL measurement. When the distribution into left heart, bronchi, pulmonary arteries, and veins is removed ETVLmean/PETW = 1.07.

Citations

Oct 1, 1985·Toxicology and Industrial Health·L W Hedlund, C E Putman
Jan 1, 1982·Annals of the New York Academy of Sciences·J M Hughes
Jan 1, 1986·Canadian Anaesthetists' Society Journal·W H Noble, J C Kay
Jan 1, 1988·European Journal of Nuclear Medicine·R Y ChuJ Myers
Oct 1, 1987·Circulation·J I SznajderA G Little
Mar 1, 1983·Canadian Anaesthetists' Society Journal·R Martineau, W H Noble
Jan 1, 1987·International Journal of Clinical Monitoring and Computing·M GrovesR Raheja
Mar 25, 2008·American Journal of Physiology. Lung Cellular and Molecular Physiology·Richard M EffrosRichard Casaburi
Jan 1, 1989·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·R Y ChuG Basmadjian
Mar 1, 1990·The Journal of Surgical Research·J C Böck, F R Lewis

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