PMID: 6105528Aug 23, 1980Paper

Reappraisal of the effects of aspirin on the stomach

Lancet
W D Rees, L A Turnberg

Abstract

In a survey of the published evidence linking aspirin ingestion to gastric mucosal damage an attempt has been made to assess the role of aspirin in the pathogenesis of acute and chronic gastric haemorrhage and peptic ulceration. It seems that aspirin ingestion rarely causes clinically significant gastric damage in normal subjects and then usually only with large or frequent doses. Even in these rare instances the specific role of aspirin remains uncertain.

References

Nov 1, 1977·The American Journal of the Medical Sciences·R R Miller, H Jick
Oct 1, 1979·Annals of Internal Medicine·G R SilvosoJ Hewett
Jan 1, 1979·Scandinavian Journal of Gastroenterology·J Deregnaucourt
Jan 18, 1969·Lancet·F O Stephens, K B Lawrenson
Feb 28, 1973·Biochimica Et Biophysica Acta·J DemanE Bruyneel
Apr 1, 1971·The American Journal of Digestive Diseases·J A Benson
Nov 8, 1973·The New England Journal of Medicine·J R LeonardsR Niemczura
Jun 1, 1968·Archives of Internal Medicine·W B ThorsenJ F Morrissey
Dec 14, 1968·British Medical Journal·H B ValmanN F Coghill
Dec 14, 1968·British Medical Journal·K Goulston, A R Cooke
Aug 9, 1969·British Medical Journal·A R Cooke, K Goulston
Oct 1, 1969·Journal of Pharmaceutical Sciences·J R Leonards, G Levy
Oct 1, 1970·Journal of Pharmaceutical Sciences·J R Leonards, G Levy
Nov 25, 1967·British Medical Journal·C E Astley
Feb 15, 1980·JAMA : the Journal of the American Medical Association
Dec 1, 1980·Circulation·P C Elwood, P M Sweetnam
Aug 1, 1956·The American Journal of the Medical Sciences·J J KELLY
Mar 10, 1962·British Medical Journal·L T STUBBE van HEULEN

Citations

Jan 1, 1987·Pharmacology & Therapeutics·R O DayJ de Jager
Aug 29, 1981·Lancet·F MornexC Partensky
Mar 1, 1985·Postgraduate Medical Journal·J Wilson-MacdonaldR C Williamson
Jan 1, 1985·Journal of Chronic Diseases·M C BelconP Tugwell
Mar 1, 1983·Pharmacotherapy·David GreenChung-Hsin Ts'ao
Mar 1, 1990·Scandinavian Journal of Primary Health Care·J Månsson
Jun 1, 1988·Alimentary Pharmacology & Therapeutics·C J HawkeyS Marshall
Mar 1, 1985·Scandinavian Journal of Gastroenterology·R I TrondstadB Olaussen
Jan 1, 1987·Scandinavian Journal of Gastroenterology. Supplement·A Malchow-Møller
Dec 1, 1987·Alimentary Pharmacology & Therapeutics·C J Hawkey
Jan 1, 1987·Acta Medica Scandinavica·L A Christensen, E B Schmidt

Related Concepts

Zorprin
Structure of Pyloric Gland
Hematochezia
Marginal Ulcer
Stomach

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