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Rearrangement of immunoglobulin genes in shark germ cells

The Journal of Experimental Medicine

May 17, 2000

S S LeeEllen Hsu

PMID: 10811858

Abstract

The variable (V), (diversity [D]), and joining (J) region recombinases (recombination activating genes [RAGs]) can perform like transposases and are thought to have initiated development of the adaptive immune system in early vertebrates by splitting archaic V genes with transposable el...read more

Mentioned in this Paper

Vertebrates
Immune System
Transposase
EFNA5 gene
Immunoglobulin Activity
Recombination, Genetic
Homologous Sequences, Amino Acid
Recombinase
Shark - fish
Immunoglobulins
2
51
Paper Details
References
  • References40
  • Citations43
1234
  • References40
  • Citations43
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Rearrangement of immunoglobulin genes in shark germ cells

The Journal of Experimental Medicine

May 17, 2000

S S LeeEllen Hsu

PMID: 10811858

DOI:

Abstract

The variable (V), (diversity [D]), and joining (J) region recombinases (recombination activating genes [RAGs]) can perform like transposases and are thought to have initiated development of the adaptive immune system in early vertebrates by splitting archaic V genes with transposable el...read more

Mentioned in this Paper

Vertebrates
Immune System
Transposase
EFNA5 gene
Immunoglobulin Activity
Recombination, Genetic
Homologous Sequences, Amino Acid
Recombinase
Shark - fish
Immunoglobulins
2
51

Feeds With Similar Papers

Transposable Elements

Transposable elements (tes) have profound effects on the structure, function and evolution of their host genomes.

Transposons for Gene Editing

Transposons can replicate and spread through the host’s genome and therefore be used as a genetic tool for analysis of gene function. Discover the latest research on the use of transposons for gene editing here.

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Paper Details
References
  • References40
  • Citations43
1234
  • References40
  • Citations43
12345

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