Recall and recognition confabulation in psychotic and bipolar disorders: evidence for two different types without unitary mechanisms

Comprehensive Psychiatry
José Salazar-FraileManuel Gómez-Beneyto

Abstract

Several forms of confabulation have been identified recently in schizophrenic patients, but it has not yet been investigated whether these forms are specific to schizophrenia. Furthermore, the origin of confabulation is unclear. The present study investigated recall and recognition confabulation and their relations with symptomatology, cognitive domains (abstraction and flexibility, verbal fluency, verbal memory, motor activity, and visual-motor processing/attention), computed tomographic (CT) measures (ventricular, cerebral, and Sylvian fissure size), and auditory event-related potentials (amplitudes and latencies of peak components in oddball paradigms) in 33 schizophrenic patients, 35 bipolar I patients, eight schizoaffective patients, and seven patients with other psychotic disorders. We found that neither type of confabulation was specific of any diagnostic group. Recall confabulation was mainly predicted by the predominance of positive symptoms, while recognition confabulation was predicted by a delay in P300 latency and the doses of antipsychotics used. Our results suggest two different mechanisms for both types of confabulation based on interference with the adequate retrieval of information and slowness in early stimul...Continue Reading

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Citations

Jun 27, 2008·The Behavioral and Brain Sciences·Bernard Crespi, Christopher Badcock
Jul 16, 2010·Journal of the International Neuropsychological Society : JINS·E Lorente-RoviraP J McKenna
Aug 1, 2014·Cognitive Neuropsychiatry·Mohammed K Shakeel, Nancy M Docherty
Oct 25, 2016·Journal of the International Neuropsychological Society : JINS·Mohammed K ShakeelAmanda McCleery

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