Recanalization of isolated chronic total occlusions in patients with stable angina

International Journal of Cardiology
Miłosz JaguszewskiAndrzej Rynkiewicz

Abstract

Despite procedural advances, recanalization of chronic total occlusions (CTOs) with percutaneous coronary intervention (PCI) remains controversial, particularly given that its long-term benefits are unclear. We assessed the association between successful PCI and symptom improvement as well as outcomes in patients with CTO and stable angina. We performed a retrospective study of 386 consecutive patients undergoing attempted PCI of an isolated CTO (i.e., no other angiographically-significant disease was present). We analyzed prospectively the change in Canadian Cardiovascular Society (CCS) classification system and occurrence of major adverse cardiovascular events (death, myocardial infarction or target vessel revascularization), after stratifying patients by procedural success. To understand which patients might benefit most from attempted PCI, multivariable models were constructed to predict: likelihood of successful PCI and symptom improvement, defined as resolution of angina or improvement of ≥ 2 CCS classes. A total of 247 (64%) patients had successful PCI. Greater symptom improvement was noted after successful PCI at both 6 months (79.8% versus 34.5% with resolution of angina or improvement of ≥ 2 CCS classes, p<0.01) and 2...Continue Reading

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Citations

Apr 18, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Hsiu-Yu FangChiung-Jen Wu
Jan 21, 2015·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Milosz JaguszewskiMarcin Gruchala
Jun 2, 2015·Current Cardiovascular Imaging Reports·Wijnand J StuijfzandPaul Knaapen
May 29, 2014·Nature Reviews. Cardiology·Loes P HoebersJosé P S Henriques
Oct 21, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·D S ChadhaShet S Arun
Jul 12, 2017·Coronary Artery Disease·Janarthanan Sathananthan, Vladimír Džavík

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