Recent advancements in esophageal cancer treatment in Japan

Annals of Gastroenterological Surgery
Yoshihiro TanakaKazuya Yamaguchi

Abstract

The 11th edition of the Japanese Classification of Esophageal Cancer (EC) was published in 2017. Some correction was made in the depth of tumor invasion to be consistent with the TNM classification by the Union for International Cancer Control (UICC). With regard to surgery, short-term safety and long-term effectiveness under thoracotomy/video-assisted thoracoscopic surgery are expected to be proven by the Japan Clinical Oncology Group (JCOG)1409 study. Results of nutritional management and countermeasures for adverse events not only during the perioperative period but also during EC chemotherapy were reported. From now on, the pursuit of low invasiveness and radicality is desired. Esophageal surgery is also expected to be safe at all institutions. To determine the optimal modality of preoperative treatment and a novel chemo(radio)therapy regimen for patients with distant metastasis, the results of the ongoing JCOG1109 and 0807 studies are being released. The effect of the addition of molecular targeted drugs on chemotherapy and concurrent chemoradiation has not yet improved overall survival. Immune checkpoint inhibitor drugs could offer a potential new treatment approach for patients with treatment-refractory advanced squamous...Continue Reading

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Citations

Dec 21, 2019·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Flávio Roberto TakedaIvan Cecconello
Feb 20, 2019·General Thoracic and Cardiovascular Surgery·Keita NakanishiKazuo Koyanagi
Jun 9, 2019·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Rui ZhangZhenming Fu
Sep 10, 2019·Osong Public Health and Research Perspectives·Yousef DouzandeganAbdolvahab Moradi
Nov 7, 2019·Nanomaterials·Kateřina ŠkrlováDaniela Plachá
Sep 24, 2020·Esophagus : Official Journal of the Japan Esophageal Society·Yoshihiro KakejiSatoshi Suzuki
Feb 4, 2021·Annals of Gastroenterological Surgery·Shigeru TakedaHiroaki Nagano
Jan 8, 2021·Langenbeck's Archives of Surgery·Masayuki UrabeHarushi Udagawa

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Methods Mentioned

BETA
dissection
surgical resection

Software Mentioned

CarPacRT
PERFECT

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