Recent advances in corpus luteum physiology

Journal of Dairy Science
M F Smith


Development, maintenance, and regression of the corpus luteum have been investigated for many years. However, endocrine and cellular mechanisms regulating progesterone synthesis and secretion remain unclear. Because comprehensive reviews of factors affecting luteal function have been published recently, this paper discusses several emerging concepts that may be important in understanding the regulation of luteal progesterone synthesis and secretion. Concepts discussed include preovulatory follicular determinants of subsequent luteal function, hormonal stimulation of progesterone synthesis, effect of different luteal cell types on progesterone secretion, and role of secretory granules in luteal function.


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