Recent advances in cytokine detection by immunosensing

Biosensors & Bioelectronics
Guozhen LiuEwa M Goldys

Abstract

The detection of cytokines in body fluids, cells, tissues and organisms continues to attract considerable attention due to the importance of these key cell signaling molecules in biology and medicine. In this review, we describe recent advances in cytokine detection in the course of ongoing pursuit of new analytical approaches for these trace analytes with specific focus on immunosensing. We discuss recent elegant designs of sensing interface with improved performance with respect to sensitivity, selectivity, stability, simplicity, and the absence of sample matrix effects. Various immunosensing approaches based on multifunctional nanomaterials open novel opportunities for ultrasensitive detection of cytokines in body fluids in vitro and in vivo. Methodologies such as suspension arrays also known as bead assays together with optical fiber-based sensors, on their own or in combination with microfluidic devices will continue to have an important role to address the grand challenge of real-time in vivo multiplex cytokine detection.

References

Feb 14, 2006·Methods : a Companion to Methods in Enzymology·Josephine H CoxSylvia Janetzki
Nov 22, 2008·Lab on a Chip·He ZhuAlexander Revzin
Oct 24, 2009·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Fatemeh Saberi HosnijehRoel Vermeulen
Jun 1, 2011·Chemical Society Reviews·Michal Hocek, Miroslav Fojta
Jun 24, 2011·Clinical and Vaccine Immunology : CVI·Elizabeth Crabb BreenPhilip J Norris
Aug 9, 2011·Accounts of Chemical Research·Michael Famulok, Günter Mayer
Jan 19, 2012·PLoS Computational Biology·Iain H Moal, Paul A Bates
Jun 2, 2012·Biomicrofluidics·Alexander RevzinH-C Chang
Jul 28, 2012·ACS Nano·Bhaskara V ChikkaveeraiahXiaoyuan Chen
Dec 4, 2012·Expert Review of Anti-infective Therapy·Qing ZhouAlexander Revzin
Apr 4, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Sunmin AhnM Selim Ünlü
May 7, 2013·ACS Applied Materials & Interfaces·Alicia L GuiJ Justin Gooding
Apr 24, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Joseph B Schlenoff
Nov 28, 2014·Chemical Communications : Chem Comm·Yingshu GuoJing-Juan Xu
Dec 4, 2014·Analytica Chimica Acta·Julie A Stenken, Andreas J Poschenrieder
Mar 21, 2015·ACS Nano·Pengyu ChenKatsuo Kurabayashi
Jun 27, 2015·The Analyst·Meral YüceHikmet Budak
Oct 10, 2015·ACS Applied Materials & Interfaces·Chun-Jen HuangT Randall Lee

❮ Previous
Next ❯

Citations

Jun 15, 2016·Biosensors & Bioelectronics·E Sánchez-TiradoJ M Pingarrón
Oct 12, 2016·Biosensors & Bioelectronics·Paria PashazadehMiguel de la Guardia
Apr 28, 2017·Sensors·Paloma Yáñez-SedeñoJosé M Pingarrón
May 11, 2017·International Journal of Inflammation·Rebecca N Monastero, Srinivas Pentyala
Feb 3, 2018·Assay and Drug Development Technologies·Wei HuangRuo-Pan Huang
Nov 16, 2017·Nature Reviews. Gastroenterology & Hepatology·Alex J ThompsonGuang-Zhong Yang
Apr 6, 2020·The Analyst·Mintra TongdeeShuichi Takayama
Dec 14, 2017·International Journal of Molecular Sciences·Helena Kupcova SkalnikovaPetr Vodicka
Jan 29, 2019·Environmental Science and Pollution Research International·Martyna Pajewska-SzmytRenata Gadzała-Kopciuch
Sep 23, 2018·Sensors·Maria Serena ChiriacòGiuseppe Maruccio
Apr 15, 2021·Expert Review of Proteomics·Paul DavidGeorg F Weber
May 23, 2021·Science Advances·Yuji GaoChwee Teck Lim
Jun 12, 2021·Advanced Science·Chao LiuGuozhen Liu
Jun 25, 2020·ACS Applied Materials & Interfaces·Laicong QiaoGuozhen Liu
Apr 12, 2019·ACS Sensors·Jennifer MoralesHeather A Clark
Aug 24, 2021·Advanced Healthcare Materials·Bernhard BurtscherCarlo A Bortolotti

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arterial-Venous in Development & Disease

Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.