Recent advances in HIV-associated Kaposi sarcoma

F1000Research
Alessia Dalla PriaMark Bower

Abstract

Kaposi sarcoma (KS) is a mesenchymal tumour caused by KS-associated herpesvirus and is an AIDS-defining illness. Despite a decline in incidence since the introduction of combination anti-retroviral therapy, KS remains the most common cancer in people living with HIV in sub-Saharan Africa, where it causes significant morbidity and mortality. This review reflects on recent epidemiological data as well as current management, unmet needs and future perspectives in the treatment of HIV-associated KS with particular emphasis on the potential role of immune checkpoint inhibitors.

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Citations

Sep 15, 2020·Clinical Hemorheology and Microcirculation·Stine LutzeAndreas Arnold
Dec 10, 2020·Journal of Immunology Research·Owen Ngalamika, Sody Munsaka
Feb 24, 2021·Disease-a-month : DM·Shailesh GondivkarKamran Habib Awan
Apr 9, 2021·Scientific Reports·Amanda de Oliveira LopesVanessa Salete de Paula
Sep 2, 2021·Scientific Reports·Gervillien Arnold MalongaAnne-Geneviève Marcelin

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