Recent advances in N-heterocyclic carbene-based radical catalysis.

Chemical Science
Takuya IshiiHirohisa Ohmiya

Abstract

In nature, a number of enzymes use thiamine diphosphate as a coenzyme to catalyze the pyruvate decarboxylation. The resultant enamine, a so-called "Breslow intermediate," is known to perform single electron transfer to various electron acceptors. Inspired by this enzymatic catalysis, N-heterocyclic carbene (NHC)-catalyzed radical reactions have been developed. This minireview highlights the recent progress and developments in NHC-based radical catalysis. This minireview is categorized according to the reaction types; oxidation type reaction and carbon-carbon bond formation through single electron transfer/radical-radical coupling.

References

Jun 12, 2003·Chemical Reviews·Stephen W Ragsdale
Oct 25, 2007·Chemical Reviews·Dieter EndersAlexander Henseler
May 22, 2008·Chemical Reviews·Ronald Kluger, Kai Tittmann
Oct 11, 2008·Angewandte Chemie·Joyram GuinArmido Studer
Jan 9, 2010·Journal of the American Chemical Society·Suman De SarkarArmido Studer
Apr 3, 2010·Organic Letters·Suman De Sarkar, Armido Studer
Oct 23, 2010·Angewandte Chemie·Suman De Sarkar, Armido Studer
Mar 2, 2012·Chemical Society Reviews·Xavier Bugaut, Frank Glorius
Jun 27, 2014·Nature·Matthew N HopkinsonFrank Glorius
Feb 5, 2015·Journal of the American Chemical Society·Yuexia ZhangYonggui Robin Chi
May 21, 2015·Chemical Reviews·Darrin M FlaniganTomislav Rovis
Aug 11, 2015·Journal of the American Chemical Society·Nicholas A White, Tomislav Rovis
Oct 1, 2015·Chemical Science·Julia RehbeinJenny Phan
Dec 19, 2018·Journal of the American Chemical Society·Vianney RegnierDavid Martin
Feb 21, 2019·Journal of the American Chemical Society·Takuya IshiiHirohisa Ohmiya
May 23, 2019·Angewandte Chemie·Dirk Leifert, Armido Studer
May 28, 2019·Angewandte Chemie·Runjiang Song, Yonggui Robin Chi
Aug 27, 2019·Journal of the American Chemical Society·Takuya IshiiHirohisa Ohmiya
Dec 10, 2019·Angewandte Chemie·Andreas MavroskoufisMatthew N Hopkinson
Mar 5, 2020·Chemical Communications : Chem Comm·Hai-Bin YangChuande Wu

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Citations

Jan 13, 2021·Organic Letters·Hai-Bin Yang, Dan-Hong Wan
Oct 10, 2020·Chemistry : a European Journal·Qing-Zhu LiJun-Long Li
May 6, 2021·Organic & Biomolecular Chemistry·Yasushi YoshidaMasami Sakamoto
Nov 27, 2020·Chemical Communications : Chem Comm·Shilpa Barik, Akkattu T Biju
Jun 8, 2021·Chemical Science·Jing LiuWen-Jing Xiao
Jun 24, 2021·Nature Communications·Yuki MatsukiHirohisa Ohmiya
Jun 8, 2021·Angewandte Chemie·Anna V BayKarl A Scheidt
Jul 17, 2021·Angewandte Chemie·Runjiang SongYonggui Robin Chi
Nov 18, 2021·Organic Letters·Yuxing CaiYong Huang
Dec 3, 2021·Physical Chemistry Chemical Physics : PCCP·Ming-Hsiu Hsieh, Jen-Shiang K Yu

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