Recent advances in neurotechnologies with broad potential for neuroscience research.

Nature Neuroscience
Abraham Vázquez-GuardadoJohn A Rogers

Abstract

Interest in deciphering the fundamental mechanisms and processes of the human mind represents a central driving force in modern neuroscience research. Activities in support of this goal rely on advanced methodologies and engineering systems that are capable of interrogating and stimulating neural pathways, from single cells in small networks to interconnections that span the entire brain. Recent research establishes the foundations for a broad range of creative neurotechnologies that enable unique modes of operation in this context. This review focuses on those systems with proven utility in animal model studies and with levels of technical maturity that suggest a potential for broad deployment to the neuroscience community in the relatively near future. We include a brief summary of existing and emerging neuroscience techniques, as background for a primary focus on device technologies that address associated opportunities in electrical, optical and microfluidic neural interfaces, some with multimodal capabilities. Examples of the use of these technologies in recent neuroscience studies illustrate their practical value. The vibrancy of the engineering science associated with these platforms, the interdisciplinary nature of this...Continue Reading

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Citations

May 14, 2021·Nature·Francis R WillettKrishna V Shenoy
May 14, 2021·Frontiers in Cellular Neuroscience·Zachary T Olmsted, Janet L Paluh
Aug 4, 2021·Advanced Healthcare Materials·Cara T MotzCheng Zhu
Sep 28, 2021·Frontiers in Neuroscience·Dimitrios FirfilionisAndrew Jackson

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Methods Mentioned

BETA
biosensing
genetic modifications
transgenic
fluorescence imaging
Fluorescence

Software Mentioned

Neurolux
Inscopix
Neurogrid
Neuralink

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