Recent advances in pharmaceutical applications of chiral capillary electrophoresis

Journal of Pharmaceutical and Biomedical Analysis
Pham Thi Thanh HaAnn Van Schepdael

Abstract

This review article summarizes developments and applications of chiral capillary electrophoresis (CE) in the pharmaceutical field published from January 2004 to June 2005. Due to the tremendous number of publications, this article is aimed to focus on major developments in chiral separations and some selected applications rather than to provide a descriptive overview of all published papers. Valuable information is also collected from several excellent reviews published during this period. Developments are classified according to CE modes, namely capillary zone electrophoresis (CZE), micellar electrokinetic capillary chromatography (MEKC), microemulsion electrokinetic chromatography (MEEKC). In the CZE section, different types of chiral selectors including cyclodextrins, oligo- and polysaccharides, crown ethers, macrocyclic antibiotics, ligand exchange systems and proteins are described. Nonaqueous capillary electrophoresis is also included in this section. Coupling CE to MS is discussed in a separate part, followed by a summary of selected pharmaceutical applications of enantioselective CE. Finally, some conclusions are drawn and prospects of CE in chiral analysis are also drafted.

References

Dec 31, 2003·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Vincenzo CucinottaGraziella Vecchio
Jan 9, 2004·Chirality·Helena DodziukAndrzej Ejchart
Feb 26, 2004·Electrophoresis·Syed Asad Ali RizviShahab A Shamsi
Feb 26, 2004·Electrophoresis·Melissa D Mertzman, Joe P Foley
Feb 26, 2004·Electrophoresis·Bertha C ValleIsiah M Warner
Mar 3, 2004·Journal of Chromatography. a·Tímea IványiYvan Vander Heyden
Jun 3, 2004·Electrophoresis·Melissa D Mertzman, Joe P Foley
Jun 24, 2004·Electrophoresis·Tao BoMarja-Liisa Riekkola
Nov 27, 2004·The Analyst·Shuji KodamaKazuichi Hayakawa
Dec 15, 2004·Electrophoresis·Alex MarshKevin Altria
May 3, 2005·Journal of Chromatography. a·Ashok Mohanty, Joykrishna Dey

❮ Previous
Next ❯

Citations

Oct 22, 2008·Analytical and Bioanalytical Chemistry·Yi LiuHuwei Liu
Dec 7, 2010·Journal of Pharmaceutical and Biomedical Analysis·Gerhard K E Scriba
Aug 3, 2010·Journal of Pharmaceutical and Biomedical Analysis·Aleksandra F ProkhorovaOleg A Shpigun
Dec 29, 2007·Electrophoresis·Laura Sánchez-HernándezCarmen García-Ruiz
Sep 27, 2008·Electrophoresis·Abolghasem Jouyban, Ernst Kenndler
Oct 30, 2008·Electrophoresis·Ahmad AminiTorbjörn Arvidsson
Jan 22, 2009·Electrophoresis·Raychelle M Burks, David S Hage
Aug 5, 2009·Electrophoresis·Peter Mikus, Katarína Maráková
Nov 13, 2009·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Yanli YangAiyou Hao
Mar 9, 2010·Electrophoresis·Anne-Catherine ServaisGerhardus J de Jong
Mar 24, 2010·Electrophoresis·Jiaquan ChenBin Chen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Cell Wall Structure (ASM)

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Bacterial Cell Wall Structure

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

© 2021 Meta ULC. All rights reserved