Recent Advances in Portable Biosensors for Biomarker Detection in Body Fluids.

Biosensors
Brian SenfJong-Hoon Kim

Abstract

A recent development in portable biosensors allows rapid, accurate, and on-site detection of biomarkers, which helps to prevent disease spread by the control of sources. Less invasive sample collection is necessary to use portable biosensors in remote environments for accurate on-site diagnostics and testing. For non- or minimally invasive sampling, easily accessible body fluids, such as saliva, sweat, blood, or urine, have been utilized. It is also imperative to find accurate biomarkers to provide better clinical intervention and treatment at the onset of disease. At the same time, these reliable biomarkers can be utilized to monitor the progress of the disease. In this review, we summarize the most recent development of portable biosensors to detect various biomarkers accurately. In addition, we discuss ongoing issues and limitations of the existing systems and methods. Lastly, we present the key requirements of portable biosensors and discuss ideas for functional enhancements.

References

Mar 23, 2001·Biosensors & Bioelectronics·D R ThévenotG S Wilson
Aug 6, 2002·The Journal of Clinical Endocrinology and Metabolism·Isao TabetaYukitaka Miyachi
Jul 2, 2003·Dental Update·Crispian Scully, Mel Rosenberg
Sep 15, 2004·Analytical and Bioanalytical Chemistry·Natalya V ZaytsevaAntje J Baeumner
Jul 29, 2008·Analytical Chemistry·Richard C StevensClement E Furlong
Feb 18, 2010·Sensors and Actuators. B, Chemical·Nicholas StrandCristina E Davis
Jan 25, 2011·Biosensors & Bioelectronics·Huanfen YaoBabak A Parviz
Apr 9, 2011·Biomedical Microdevices·MingXing ChuKohji Mitsubayashi
May 13, 2011·Journal of the American Chemical Society·B Scott FergusonH Tom Soh
Aug 19, 2011·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Richard B Reilly, T Clive Lee
Aug 30, 2011·Journal of Virological Methods·Ronghui WangYanbin Li
Jul 14, 2012·Analytica Chimica Acta·Marco RighettoniSotiris E Pratsinis
Sep 3, 2017·Biosensors & Bioelectronics·Savannah AfsahiBrett R Goldsmith
Oct 17, 2017·Biosensors & Bioelectronics·Lewis A FraserJulian A Tanner
Oct 19, 2017·Scientific Reports·David KinnamonShalini Prasad
Mar 3, 2018·Toxicology and Applied Pharmacology·Amin S M SalehiBradley C Bundy
Sep 15, 2018·Bioconjugate Chemistry·Marissa A Morales, Jeffrey Mark Halpern
Jan 6, 2019·Materials·Hoang Hiep NguyenMoonil Kim
May 17, 2019·Biosensors & Bioelectronics·Juliane R SempionattoJoseph Wang
Oct 2, 2019·Analytical Chemistry·Laura García-CarmonaAlberto Escarpa
Nov 15, 2019·Science Advances·Wenya HeYingying Zhang

Methods Mentioned

BETA
biosensors
biosensor
chip
surface plasmon resonance
enzyme capture assay
biosensing

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Nodding Syndrome

Nodding Syndrome is a neurological and epileptiform disorder characterized by psychomotor, mental, and growth retardation. Discover the latest research on Nodding Syndrome here.

LRRK2 & Microtubules

Mutations in the LRRK2 gene are risk-factors for developing Parkinson’s disease (PD). LRRK2 mutations in PD have been shown to enhance its association with microtubules. Here is the latest research.

Related Papers

IEEE Transactions on Bio-medical Engineering
Journal of Biotechnology
F Scheller
Current Opinion in Biotechnology
G G Guilbault
ASAIO Transactions
W H Ko
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme
M Aizawa
© 2021 Meta ULC. All rights reserved