Recent advances in proteomic studies of adipose tissues and adipocytes

International Journal of Molecular Sciences
Eun Young KimKwang-Hee Bae

Abstract

Obesity is a chronic disease that is associated with significantly increased levels of risk of a number of metabolic disorders. Despite these enhanced health risks, the worldwide prevalence of obesity has increased dramatically over the past few decades. Obesity is caused by the accumulation of an abnormal amount of body fat in adipose tissue, which is composed mostly of adipocytes. Thus, a deeper understanding of the regulation mechanism of adipose tissue and/or adipocytes can provide a clue for overcoming obesity-related metabolic diseases. In this review, we describe recent advances in the study of adipose tissue and/or adipocytes, focusing on proteomic approaches. In addition, we suggest future research directions for proteomic studies which may lead to novel treatments of obesity and obesity-related diseases.

References

Jul 4, 2002·Molecular & Cellular Proteomics : MCP·Irina KratchmarovaAkhilesh Pandey
Jan 17, 2003·Molecular and Cellular Biology·Leanne Wilson-FritchSilvia Corvera
Mar 30, 2004·Proteomics·Gavin I WelshJeremy M Tavaré
Feb 19, 2005·Cellular and Molecular Life Sciences : CMLS·J RenesE Mariman
Mar 9, 2005·Molecular & Cellular Proteomics : MCP·James P DeLanyJeffrey M Gimble
Oct 5, 2006·Molecular & Cellular Proteomics : MCP·Sanjin ZvonicJeffrey M Gimble
Dec 15, 2006·Nature·Jean-Pierre Després, Isabelle Lemieux
Jan 6, 2007·Journal of Proteome Research·Rachel NavetFrancis E Sluse
Mar 22, 2007·Journal of Lipid Research·Jaswinder K Sethi, Antonio J Vidal-Puig
Dec 14, 2007·Nature·Benjamin F CravattJohn R Yates
Feb 13, 2008·Proceedings of the National Academy of Sciences of the United States of America·Marcus KrügerMatthias Mann
Feb 26, 2008·Proteomics·Wei YangMichael R Freeman
Aug 30, 2008·Genomics·Debashis Ghosh, Laila M Poisson
Oct 25, 2008·Journal of Proteome Research·Henrik MolinaAkhilesh Pandey
Apr 7, 2009·Cellular and Molecular Life Sciences : CMLS·J KimB-M Kwon
Apr 9, 2009·Biochemical and Biophysical Research Communications·Hyeyun JungSang Chul Lee
Aug 18, 2009·Expert Review of Proteomics·Belén PeralJuan Antonio López
Jul 14, 2010·Nature Biotechnology·Parag Mallick, Bernhard Kuster
Aug 17, 2010·Journal of Proteome Research·Jun ZhongAkhilesh Pandey
Dec 8, 2010·Gerontology·Christoph H SaelyHeinz Drexel
Mar 29, 2011·Journal of Proteomics·Arturo Roca-RivadaMaría Pardo
Jun 17, 2011·Journal of Cellular Biochemistry·Feng YeJian-Bin Tong
Aug 6, 2011·Journal of Proteome Research·Billy W NewtonArul Jayaraman
Sep 29, 2011·Molecular & Cellular Proteomics : MCP·Stefan LehrJuergen Eckel

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Citations

Mar 21, 2019·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Katharina HoerstSarah Hedtrich
Dec 29, 2017·Analytical and Bioanalytical Chemistry·Peter E FeistAmanda B Hummon
Mar 30, 2017·Experimental and Therapeutic Medicine·Xiaojuan ZhuGuodong Zheng
Oct 27, 2020·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Liang ZhaoFeng Zhou

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Methods Mentioned

BETA
RNA-seq
biopsies
glycosylation
electrophoresis
acetylation
SGBS
immunoprecipitation

Software Mentioned

vWAT
MudPIT
sWAT

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