Recent advances in small molecule microarrays: applications and technology

Combinatorial Chemistry & High Throughput Screening
D P Walsh, Y T Chang

Abstract

The field of Small Molecule Microarray's (SMM's) is an ever-expanding part of the larger microarray field. SMM's are array based detection systems that use small molecules as probes immobilized on a variety of microarray surfaces that are screened against a number of targets for purposes including, but not limited to, protein-small molecule ligand recognition and protein function profiling. This review covers the recent advances in the field with particular emphasis on the successful applications of SMM's, as well as technical advances in platform optimization and novel small molecule immobilization strategies.

Citations

May 31, 2007·Chemical Society Reviews·Lourdes Basabe-DesmontsMercedes Crego-Calama
Sep 6, 2012·Organic & Biomolecular Chemistry·Thanit PraneenararatHelen E Blackwell
Feb 19, 2014·Current Opinion in Chemical Biology·Jiyoung A HongAngela N Koehler
Oct 28, 2005·Journal of Molecular Recognition : JMR·Rebecca L Rich, David G Myszka
Jun 24, 2006·Drug Discovery Today·Haiching Ma, Kurumi Y Horiuchi
May 13, 2006·Microbes and Infection·Helena I M Boshoff, Ujjini H Manjunatha
Sep 7, 2016·International Journal of Analytical Chemistry·Riccarda AntiochiaFranco Mazzei
Dec 3, 2014·Current Protocols in Chemical Biology·Marius S PopAngela N Koehler
May 2, 2020·Chemical Reviews·Christin BednarekStefan Bräse
Apr 4, 2006·Analytical Chemistry·Naoki KanohHiroyuki Osada
Jun 15, 2006·Chemical Reviews·Daniel P Walsh, Young-Tae Chang

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