Recent advances in the fabrication, functionalization, and bioapplications of peptide hydrogels.

Soft Matter
Yan WangGang Wei

Abstract

Self-assembled peptide-based nanomaterials have exhibited wide application potential in the fields of materials science, nanodevices, biomedicine, tissue engineering, biosensors, energy storage, environmental science, and others. Due to their porous structure, strong mechanical stability, high biocompatibility, and easy functionalization, three-dimensional self-assembled peptide hydrogels revealed promising potential in bio-related applications. To present the advances in this interesting topic, we present a review on the synthesis and functionalization of peptide hydrogels, as well as their applications in drug delivery, antibacterial materials, cell culture, biomineralization, bone tissue engineering, and biosensors. Specifically, we focus on the fabrication methods of peptide hydrogels through physical, chemical, and biological stimulations. In addition, the functional design of peptide hydrogels by incorporation with polymers, DNA, protein, nanoparticles, and carbon materials is introduced and discussed in detail. It is expected that this work will be helpful not only for the design and synthesis of various peptide-based nanostructures and nanomaterials, but also for the structural and functional tailoring of peptide-based ...Continue Reading

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Citations

Dec 8, 2020·Soft Matter·Yiğitcan SümbelliRıdvan Say
Mar 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Andrea CaporaleMichele Saviano
May 7, 2021·Macromolecular Bioscience·Rebecca LaceRachel L Williams
Jun 3, 2021·Bioengineering·Aleksey D Drozdov, Jesper deClaville Christiansen
Jul 29, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yuhong QianZhuang Li
Sep 4, 2021·Journal of the Mechanical Behavior of Biomedical Materials·Jacek K WychowaniecAlberto Saiani
Sep 9, 2021·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Carlo DiaferiaAntonella Accardo

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Methods Mentioned

BETA
biosensors
Rheology
chips
biosensor
transfect
transfection

Software Mentioned

NapFFRGD

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