Recent advances in the field of transition metal dichalcogenides for biomedical applications

Nanoscale
Vipul Agarwal, Kaushik Chatterjee

Abstract

Nanosheets of transition metal dichalcogenide (TMDs), the graphene-like two-dimensional (2D) materials, exhibit a unique combination of properties and have attracted enormous research interest for a wide range of applications including catalysis, functional electronics, solid lubrication, photovoltaics, energy materials and most recently in biomedical applications. Their potential for use in biosensors, drug delivery, multimodal imaging, antimicrobial agents and tissue engineering is being actively studied. However, the commercial translation of exfoliated TMDs has been limited due to the low aqueous solubility, non-uniformity, lack of control over the layer thickness, and the long-term colloidal stability of the exfoliated material. There is wide interest in the synthesis and exfoliation of TMDs resulting in the reporting of increasing numbers of new methods and their biomedical applications. The unique physicochemical characteristics of the TMD nanosheets have been exploited to tether them with biological payload to achieve selective localized delivery in vivo. The large surface-to-volume ratio, good cytocompatibility, ease of surface modification, tunable bandgap, strong spin-orbit coupling, and high optical and thermal conv...Continue Reading

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Methods Mentioned

BETA
imaging techniques
mechanical shearing
chemical vapor deposition
biosensing
X-ray
xenograft
AFM
biosensors
biosensor
fluorescence

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