Recent advances in the treatment of pancreatic cancer

F1000Research
Marc T RothJordan D Berlin

Abstract

Pancreatic ductal adenocarcinoma is one of the deadliest solid tumor malignancies and is projected to become a leading cause of cancer-related death in coming years. Improving quality of life and survival amongst these patients will require new ideas and novel therapies in a multidisciplinary approach. This review will cover the most recent advances in the comprehensive treatment of pancreatic cancer and place them within a historical context when necessary. Treatment of all disease stages will be discussed, but the focus is on systemic therapy as novel drugs and new treatment combinations enter the clinic. This will include more aggressive chemotherapy in earlier disease stages, approved uses for immunotherapy, and targetable mutations. In addition, negative trials of importance and controversial topics will be noted.

References

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Citations

Jun 25, 2021·World Journal of Gastroenterology : WJG·Nikhil Gupta, Raghav Yelamanchi
Apr 25, 2021·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Kim A Reiss, Robert H Vonderheide

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Clinical Trials Mentioned

NCT01964430
NCT03504423
NCT02125136
NCT02562716
NCT02047513
NCT02839343

Software Mentioned

NEONAX

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Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

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