Jun 18, 2004

Recent advances in the treatment of the spondyloarthropathies

Current Opinion in Rheumatology
Yan LiuMillicent A Stone


Recently, there has been renewed interest in the spondyloarthropathy family of chronic inflammatory rheumatic conditions, which has been fueled to a large extent by the biologic era. Over the period of the past 2 years in particular, there have been several notable advances. First, there have been a number of large, high-quality randomized controlled trials evaluating the tumor necrosis factor (TNF) blockers and conservative treatments such as physiotherapy and nonsteroidal anti-inflammatory drugs for use in spondyloarthropathy. This has paved the way for the development of better tools to assess outcome in these patients both in daily practice and in the context of clinical trials. This review uses a systematic approach to outline the most recent (within the last 2 years) and the most pertinent advances in the treatments of the spondyloarthropathies, with particular emphasis on ankylosing spondylitis and psoriatic arthritis. Supervised group exercise programs maintain flexibility and posture in patients with ankylosing spondylitis, and spa therapy is a cost-effective treatment option in ankylosing spondylitis. Nonsteroidal anti-inflammatory drugs have a role in symptom modification and, more importantly, may prevent structural...Continue Reading

Mentioned in this Paper

Tumor Necrosis Factor-alpha
Analgesics, Anti-Inflammatory
Anti-Inflammatory Agents, Non-Steroidal
Posture brand of calcium phosphate, tribasic
TNF gene
Tumor Necrosis Factors
Rheumatic Fever
Ankylosing Spondylitis
Clinical Trial [Publication Type]

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