Recent advances in the treatment of psoriasis

Dermatologic Clinics
C Guzzo

Abstract

We have seen great progress in the past decade in our understanding of the pathogenesis of psoriasis. The fruits of this knowledge are being realized in many of the exciting immunologic therapies currently in development. The potential for astute clinical observation to produce effective therapies and to change the direction of research has been proven in the past and still remains as an avenue for the future. Although individual treatments were discussed in this article, combination therapy is likely to continue to play a major role. Additionally, because future therapeutic developments are not likely to be free of toxicity, rotational therapy may still be necessary. Many questions remain unanswered. Substantial progress is just beginning into the.

References

Apr 16, 1992·The New England Journal of Medicine·N M GrahamJ P Phair
Nov 1, 1992·Journal of the American Academy of Dermatology·D N Kolbach, C Nieboer
Nov 1, 1992·The British Journal of Dermatology·M J KorstanjeT J Stoof
Nov 1, 1992·The British Journal of Dermatology·E PicotJ Meynadier
Dec 1, 1992·Journal of the American Academy of Dermatology·K Kragballe
May 1, 1991·The Journal of Dermatology·T NogitaA Hidano
Jan 31, 1991·The New England Journal of Medicine·C N EllisT G Parish
Feb 1, 1991·Archives of Dermatology·H J NielsenJ Georgsen
Sep 12, 1987·Lancet·M DuvicG W Brewton
Apr 1, 1989·Archives of Dermatology·A K GuptaW J McCune
Sep 1, 1988·Journal of the American Academy of Dermatology·H GollnickE Hoting
Dec 12, 1986·JAMA : the Journal of the American Medical Association·C N EllisT M Annesley
Dec 1, 1988·The British Journal of Dermatology·C GreenB E Johnson
Dec 1, 1986·The British Journal of Dermatology·J M Marks
Jan 1, 1983·The British Journal of Dermatology·J E FrakiK H Singer
Sep 1, 1982·Dermatologica·D Wallach, F Cottenot
Jul 1, 1982·The British Journal of Dermatology·N J LoweD Russell
Sep 1, 1981·Archives of Dermatology·P R Long, O F Miller
Apr 1, 1994·Journal of the American Academy of Dermatology·T Esgleyes-RibotM Duvic
Jan 1, 1994·Dermatology : International Journal for Clinical and Investigative Dermatology·A I Lauerma, H I Maibach
Jul 1, 1994·Immunology Today·C H JuneC B Thompson
Sep 1, 1993·Journal of the American Academy of Dermatology·C N EllisJ E Wolf
Jun 1, 1995·Journal of the American Academy of Dermatology·B L TownsendM Duvic
Mar 1, 1995·Clinics in Dermatology·C H Smith, J N Barker
Mar 1, 1995·Clinics in Dermatology·H Traupe
May 1, 1994·International Journal of Dermatology·J Thivolet, J F Nicolas
Sep 27, 1994·Proceedings of the National Academy of Sciences of the United States of America·J C ChangD J Carlo
Aug 11, 1994·The New England Journal of Medicine·J F BurkeJ C West
Sep 1, 1994·Journal of the American Academy of Dermatology·A N EliasM M Goodman
Jan 1, 1994·Archives of Dermatological Research·F AubinP Agache
Jan 1, 1994·The British Journal of Dermatology·E L Speight, P M Farr
Jul 1, 1993·Journal of the American Academy of Dermatology·A N EliasR J Barr
Jan 1, 1993·Dermatology : International Journal for Clinical and Investigative Dermatology·A N EliasR J Barr
Feb 1, 1993·Journal of the American Academy of Dermatology·K StorbeckG Plewig
Feb 1, 1993·Immunology Today·R L WongK D Cooper
May 1, 1993·Journal of the American Academy of Dermatology·L WitkampM M Meinardi
Jun 24, 1993·The New England Journal of Medicine·G G Krueger
Sep 1, 1995·Journal of Clinical Pharmacology·C A ElderK Simpson

❮ Previous
Next ❯

Citations

Aug 16, 2000·Dermatologic Clinics·S ProdanovichJ R Taylor
Mar 5, 1999·International Journal of Dermatology·M Lebwohl
Jan 29, 2000·International Journal of Dermatology·M V BalagonG P Walsh
Aug 3, 2006·Journal of Clinical Pharmacy and Therapeutics·A Damasiewicz-BodzekB Suwała-Jurczyk
Jan 7, 2000·The American Journal of Medicine·K G Linden, G D Weinstein
Sep 5, 2006·International Journal of Pharmaceutics·Hongzhuo LiuHuimin Yao
Feb 22, 2017·Luminescence : the Journal of Biological and Chemical Luminescence·P S HemneV Singh
Mar 24, 2000·The British Journal of Dermatology·H Gollnick, A Menter

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.