Recent Advances in Tracking the Transplanted Stem Cells Using Near-Infrared Fluorescent Nanoprobes: Turning from the First to the Second Near-Infrared Window

Advanced Healthcare Materials
Guangcun ChenQiangbin Wang

Abstract

Stem cell-based regenerative medicine has attracted tremendous attention for its great potential to treat numerous incurable diseases. Tracking and understanding the fate and regenerative capabilities of transplanted stem cells is vital for improving the safety and therapeutic efficacy of stem cell-based therapy, therefore accelerating the clinical application of stem cells. Fluorescent nanoparticles (NPs) have been widely used for in vivo tracking of the transplanted stem cells. Among these fluorescent NPs, near-infrared (NIR) NPs have greatly improved the sensitivity, tissue penetration depth, spatial and temporal resolutions of the fluorescence imaging-based stem cell tracking technologies due to the reduced absorption, scattering, and autofluorescence of NIR fluorescence in tissues. Here, this review summarizes the recent studies regarding the tracking of transplanted stem cells using NIR NPs and emphasizes the recent advances of fluorescence imaging in the second NIR window (NIR-II, 1000-1700 nm). Furthermore, the challenges and future prospects of the NIR NP-based technologies are also discussed.

References

Dec 9, 2003·Nature Biotechnology·Sungjee KimJohn V Frangioni
Feb 28, 2006·Nature Biotechnology·Min-Kyung SoJianghong Rao
Feb 22, 2008·Nature·Vincent F M Segers, Richard T Lee
Jan 9, 2009·Current Pharmaceutical Design·Yan ZhangJean N DaSilva
Jun 23, 2009·Stem Cells·Froilán Granero-MoltóAnna Spagnoli
Nov 10, 2009·Nature Nanotechnology·Andrew M SmithShuming Nie
Jan 19, 2010·Journal of the American Chemical Society·Yaping DuQiangbin Wang
Feb 6, 2010·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Erhan I Altinoğlu, James H Adair
May 6, 2010·Journal of the American Chemical Society·Nan MaJianghong Rao
Sep 18, 2010·Tissue Engineering. Part B, Reviews·Chiara VillaYvan Torrente
Sep 29, 2011·Nature Reviews. Clinical Oncology·Moritz F KircherJan Grimm
Dec 14, 2011·Journal of the American Chemical Society·Yi-Ping GuDai-Wen Pang
Dec 20, 2011·Nature Nanotechnology·Vadym N MochalinYury Gogotsi
Jan 20, 2012·Nature·Daisy A Robinton, George Q Daley
Jan 16, 2013·Proceedings of the National Academy of Sciences of the United States of America·Melissa N McCrackenOwen N Witte
Jul 23, 2013·Nature Communications·D J NaczynskiP V Moghe
Aug 16, 2013·Theranostics·Yaqi WangHooisweng Ow
Dec 5, 2013·Stem Cells Translational Medicine·Jinling MaJeroen J J P van den Beucken

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Citations

Apr 27, 2019·Advanced Materials·Shoujun ZhuHongjie Dai
Jun 19, 2019·Organic & Biomolecular Chemistry·Tong ChenShaobing Zheng
Aug 20, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xueping KongLixin Wu
Feb 23, 2020·Frontiers in Bioengineering and Biotechnology·Jie CaoHuanghao Yang
May 10, 2019·Science and Technology of Advanced Materials·Shanmugavel Chinnathambi, Naoto Shirahata
Feb 22, 2021·Biomaterials·Yingbin SuYouqing Shen
Jun 13, 2021·Advanced Materials·Caiping DingXiaoyuan Chen
Jun 24, 2021·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Dipendra DahalDipanjan Pan
Aug 12, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xueqian ChenXueyun Gao
Aug 14, 2020·Journal of the American Chemical Society·Chunyan LiQiangbin Wang
Nov 7, 2021·Current Osteoporosis Reports·Arvind HariharanSimon D Tran
Feb 6, 2022·Stem Cell Reviews and Reports·Chun-Ran XueYang-Tai Guan

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