Recent advances in understanding and managing diverticulitis

F1000Research
Carola SeveriBruno Annibale

Abstract

In the past few decades, the increasing socioeconomic burden of acute diverticulitis (AD) has become evident, and with the growth of the population age, this significant economic impact will likely continue to rise. Furthermore, recent evidence showed an increased rate of hospital admissions especially evident among women and younger individuals. The natural history and pathophysiology of this clinical condition is still to be fully defined, and efforts continue to be made in the identification of risk factors and the establishment of relative preventive strategies. The actual therapeutic strategies aimed to modulate gut microbiota, such as rifaximin or probiotics, or to reduce mucosal inflammation, such as mesalazine, present a relatively poor efficacy for both the prevention of the first AD episode (primary prevention) and its recurrence (secondary prevention). In the last few years, the main goal achieved has been in the management of AD in that uncomplicated AD can, to a larger extent, be managed in an outpatient setting with no or little supportive therapy, a strategy that will certainly impact on the health costs of this disease. The problem of AD recurrence remains a topic of debate. The aim of this review is to present ...Continue Reading

References

Mar 1, 1985·Gut·J Whiteway, B C Morson
Aug 25, 1999·The British Journal of Surgery·H TønnesenH Moller
Feb 28, 2004·Lancet·Neil Stollman, Jeffrey B Raskin
Mar 24, 2005·The American Journal of Gastroenterology·Andreas M KaiserRobert W Beart
Jan 20, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Laura W Lamps, Whitfield L Knapple
Feb 15, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M GolderH A Navsaria
Aug 30, 2008·JAMA : the Journal of the American Medical Association·Lisa L StrateEdward L Giovannucci
Nov 11, 2008·Gastroenterology·Lisa L StrateEdward L Giovannucci
Nov 26, 2008·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Olegas DeduchovasDainius H Pauza
Apr 16, 2009·The American Journal of Gastroenterology·Lisa L StrateEdward L Giovannucci
May 21, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·J SimpsonR C Spiller
Dec 31, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·T WedelM Böttner
Mar 3, 2011·European Radiology·Adrienne van RandenUNKNOWN OPTIMA Study Group
Apr 8, 2011·World Journal of Gastroenterology : WJG·Geoffrey C NguyenNitasha Anand
May 10, 2011·Langenbeck's Archives of Surgery·Burkhard H A von RahdenMartin Grimm
Aug 20, 2011·Obesity·Anders GummessonBjörn Carlsson
Sep 10, 2011·Diseases of the Colon and Rectum·Giovanni MaconiBruno Annibale
Feb 1, 2012·The British Journal of Surgery·A ChabokUNKNOWN AVOD Study Group
May 11, 2012·Digestive Diseases·Martina Böttner, Thilo Wedel
May 11, 2012·Digestive Diseases·Gabrio Bassotti, Vincenzo Villanacci
May 11, 2012·Digestive Diseases·Lisa L Strate
Aug 14, 2012·Gastroenterology·Anne F PeeryNicholas J Shaheen
Sep 14, 2012·Journal of Clinical Gastroenterology·Ivan TattoliCarola Severi
Oct 10, 2012·Free Radical Biology & Medicine·Paola MatarreseCarola Severi
Oct 25, 2012·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Angel LanasFermín Mearin
Mar 26, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Erica CohenBrennan Spiegel
Apr 18, 2013·The British Journal of Surgery·N C BuchsP Gervaz
Jul 17, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Kamyar ShahediBrennan Spiegel
Aug 21, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Lillias H MaguireAndrew T Chan
Aug 24, 2013·Digestive Surgery·Caroline S AndewegUNKNOWN Working group from Netherlands Societies of Internal Medicine, Gastroenterologists, Radiology, Health echnology Assessment a
Oct 12, 2013·Journal of Gastroenterology·Ines HellwigThilo Wedel
Dec 11, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C L KvasnovskyI Bjarnason
Dec 18, 2013·Nature·Lawrence A DavidPeter J Turnbaugh
Jan 5, 2014·Gut·Francesca L CroweUNKNOWN Million Women Study Collaborators
Jan 17, 2014·JAMA : the Journal of the American Medical Association·Arden M MorrisSamantha Hendren
Mar 13, 2014·Diseases of the Colon and Rectum·Lidewine DanielsMarja A Boermeester

❮ Previous
Next ❯

Citations

Jul 28, 2019·Techniques in Coloproctology·M Carabotti, B Annibale
May 1, 2021·Journal of Personalized Medicine·Andrea PiccioniFrancesco Franceschi
Nov 2, 2021·Visceral Medicine·Stephan K Böhm

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved